Multi Celluar Part ttwo Flashcards
What if Meiosis goes Wrong ?
Down syndrome caused by extra copy of chromosomes 21, usually resulting from non-disjunction during meiosis 1 in the female ovary ,segregation errors during meiosis increases greatly with advancing material age
Differences between Sperm and Egg ?
Sperm :
- Specialised for movement
- One of the smallest cells
Egg :
- Able to generate all cells in the body when activated usually by fertilisation
- Nutrients for the first few rounds of cell division , one of the cell types
What does the Chromosomes ?
Segregate in Anaphase A and B
The sudden loss of sister -chromatid cohesion at the onset of anaphase leads to sister -chromatid sequence separation
Allowing the forces of the mitotic spindle to pull te sisters to opposite poles of the cell
Chromosomes move by two independent and overlapping processes
First Anaphase /Second Anaphase
Initial polward of movement of chromosomes , due to shortening pole ward of kinetochore microtubules
Second Anaphase B Seperation of the spindle poles themselves , beginning after sister chromatids have separated and the daughter chromosomes , moved some distance apart
Segregated chromosomes are packaged in Daughter nuclei telophase .Daughter chromosomes have segregated into two equal group at opposite eneds of the cell
Telephase - Two sets of chromosomes are packaged into pair of daughter nuclei
What does M- cdk AND Spindle Formation do ?
M-CDK
- Triggers events of early mitosis , including chromosomes condensation , assembly of the mitotic spindle and bi polar attachment of the sister chromatid pairs of microtubules of the spindle
Spindle Formation
- In animal dependent on the largely on the ability of mitotic environment to stimulate local microtubule .Nucletion and stability as well as the ability of motor proteins