MT4 - Respiratory pasteurellosis of cattle (W) Flashcards
Pasteurella bovis can cause pasteurellosis in cattle
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- P. multocida A, (D), M. haemolytica A1, A2
Diarrhoea is the main clinical sign of bovine pasteurellosis
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fever, anorexia, nasal/ ocular discharge , death
Overcrowding is a predisposing factor of respiratory pasteurellosis of cattle
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- transportation
- starvation, cold, thirst
- nutrition, overcrowding
The lesions of respiratory pasteurellosis of calves are generally in the diaphragmatic lobes
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mainly in the anterior lobes ( fibrinous pneumonia)
Dermonecrotoxin of the agents is responsible for the clinical signs of respiratory pasteurellosis of cattle
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in swine
Primary pasteurellosis diseases are caused by obligate pathogenic Pasteurella bacteria
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facultatively anaerobic: they can survive with or without oxygen
Respiratory pasteurellosis occurs only among cattle above 6 months of age
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1-3 months (endemic form)
Toxoid vaccines can be used for the prevention of respiratory pasteurellosis of cattle
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Toxoid vaccines (M. haemolytica)
killed vaccines: (P. multocida, M. haemolytica, H. somni)
The lesions of respiratory pasteurellosis of calves are generally in the diaphragmatic lobes
F
mainly in the anterior lobes ( fibrinous pneumonia)
Pasteurella multocida can cause pasteurellosis in cattle
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* P. multocida A, (D), M. haemolytica A1, A2
mannheimia haemolytica can cause respiratory pasteurellosis of calves
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* P. multocida A, (D), M. haemolytica A1, A2
Mannheimia haemolytica can cause pasteurellosis in cattle
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* P. multocida A, (D), M. haemolytica A1, A2
Respiratory pasteurellosis can occur after transport.
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- starvation, cold, thirst
- nutrition, overcrowding
- transportation
Mannheimia haemolytica is an important agent of shipping fever
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Leukotoxin of M. haemolytica damages the alveolar macrophages
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M. haemolytica
- cytotoxin production–> damage of the macrophages
- production of prostaglandin, mediators
- formation of thrombi, necrosis
Interstitial pneumonia is a frequent post mortem lesion of pulmonary pasteurellosis of
cattle
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Fibrinous Pneum
The pneumonic lesions in the case of pulmonary pasteurellosis of cattle can be seen mainly
in the diaphragmatic lobe.
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mainly in the anterior lobes ( fibrinous pneumonia)
Salmonellosis can predispose cattle to pasteurellosis
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infectious predisposing factors:
- virus infections (PI-3, IBR, adenoviruses, RS, BVD)
- Mycoplasma, Chlamydia
Transportation can predispose cattle to pasteurellosis
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- transportation
- starvation, cold, thirst
- nutrition, overcrowding
Bovine pasteurellosis cannot be prevented with vaccination.
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- toxoid vaccines: M. haemolytica
- killed vaccines: P.multocida
Respiratory pasteurellosis has been already eradicated in Europe
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Mannheimia haemolytica is a causative agent of respiratory pasteurellosis
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Transportation is a predisposing factor of respiratory pasteurellosis of cattle.
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- transportation
- starvation, cold, thirst
- nutrition, overcrowding
There are no vaccines for the prevention of respiratory pasteurellosis of cattle
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- toxoid vaccines: M. haemolytica
- killed vaccines: P.multocida
Mycoplasmas can predispose cattle to respiratory pasteurellosis
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infectious predisposing factors:
- virus infections (PI-3, IBR, adenoviruses, RS, BVD)
- Mycoplasma, Chlamydia
The lesions of bovine respiratory pasteurellosis are generally seen in the diaphragmatic
lobes
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mainly in the anterior lobes: fibrinous pneumonia
Respiratory pasteurellosis in cattle is caused by P. multocida A and M. haemolytica A
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Most importance virulence factor of M. haemolytica is leukotoxin
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Leukotoxin is responsible for damaging leukocytes (white blood cells)
Respiratory pasteurellosis in cattle is a common disease of young animals.
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Macrolides are recommended to use in case of respiratory pasteurellosis in cattle.
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Treatment:
- isolation of clinically ill animals
- antibiotic treatment: tetracyclines, fluoroquinolones, macrolides
- elimination of predisposing factors
Respiratory pasteurellosis of cattle appears in calves aged 1-3 months old
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endemic calves 1-3m
adults - sporadic
Respiratory pasteurellosis of cattle causes a fibrinous inflammation of serous membranes
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characterized by inflammation of the lungs and bronchi,
Leukotoxin of M. haemolytica strains responsible for Pasteurella pneumonia attacks respiratory epithelium.
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Respiratory pasturellosis of cattle are mostly seen in the tropics
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Respiratory pasteurellosis of cattle causes purulent pneumonia.
F- A (fibrinous)
We can use ELISA to diagnose respiratory pasteurellosis in cattle
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detection of the agent:
* isolation, identification
* IF, PCR
detection of antibodies:
* ELISA, immunoblot, passive HA
detection of possible primary pathogens:
* direct detection of the agents
* serology (paired samples)
A predisposing factor of respiratory pasteurellosis in cattle is transport.
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A predisposing factor of respiratory pasteurellosis in cattle is the presence of a viral infection.
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virus infections:
- PI-3, IBR, adenoviruses
- RS, BVD
- Mycoplasma, Chlamydia
Lesions of respiratory pasteurellosis of calves are seen in the anterior lobes
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Vaccination is widely used for prevention of bovine respiratory pasteurellosis..
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