MSK Flashcards
What is DISH /
Diffuse idiopathic skeletal hyperostosis - anterior osteophtes spanning at least 4 vertebral levels with normal disc space and sacroiliac joints.
Associated with calcification of the posterior longitudinal ligament
What is kümmel disease ?
Gas within the vertebral body secondary to osteonecoriss from a compression fracture
What does the seagull sign refer to ?
erosive OA of the DIPJ - due to marginal osteophytes and medial erosion
In the hip joint, if there is AXIAL loss of space what does that usually mean ?
Associated with RA, however OA is still more common than RA in the hip
What is Protrusio deformity ?
More than 3mm or 6mm medial migration of the femoral head at the ilioishchial line
What joint is most commonly affected in the foot with RA ?
Metatarsalphalangeal joints
Which way do the joints subluxation in RA at the MCP ?
Ulna deviation
Why is only the inferior aspect of the sacroiliac joint affected in spodyloarthropathies ?
Because only the inferior portion is synovial.
What causes symmetrical sacroilitis ?
IBD associated arthropathy and ankylosing spondylitis
What causes asymmetrical sacroilitis ?
Psoriatic arthritis and reactive athropathy
What does the shiny corner sign signify?
Evolution of a prior Romans lesion
What is a Romanus lesion?
Erosion of the anterior/posterior edge of a vertebral body, early sign of a spondyloarthropathy
What is the dagger sign ?
Fusion of the spinous process - associated with ankylosing spondylosis
What other medical conditions is Ankylosing spondylitis assoicated with ?
pulmonary fibrosis
Aortitis
Cardiac conduction defects
What is the earliest signs of AS ?
Symmetrical erosions, widening and sclerosis of the sacroiliac joints
What is an Andersson lesions ?
Inflammatory involvement of the invertebrate disc by a spondyloarthropathy
Where does psoriatic arthritis commonly affect ?
The hands
What hands signs are classicaclly seen in psoaratic arthritis ?
Sausage digit
Pencil in cup
What conditions can lead to arthritis mutilans ? what is the classic hand finding ?
Psoriatic arthritis and rheumatoid
Telescoping of the fingers
What foot sign is seen in psoriatic arthritis ?
Ivory phalanx
What does reactive arthritis commonly affect ?
Knee, feet,
What is the key radiographic finding of SLE ?
Reducible subluxations of the MCP and PIP with abscence or erosive change
What is the characteristic sign of scleroderma ?
Acro-osteolysis - reabsorption of the distal portion of the distal phalanges + calcification
What type of crystals are deposited in calcium pyrophosphate ?
Rhomboid crystals are positively birefringent
What conditions are associated with calcium pyrophosphate ?
Haemochromatosis, hyperparathyroidism and hypophosphatasia
What causes osteomalacia ?
Most common is vitamin D deficiency
Which spinal cord lesions cause a dumbbell shaped tumour ?
Meningioma
Schwannomas
Neurofibromas
Ganglioneuroma
Neuroblastoma
What is the cockade sign ?
Calacaenal interosseous lipoma - well defined lytic lesion with central calcification
What is the arcuate sign ?
Avulsion fracture of the fibulae styloid - where the arcuate ligament attaches
This ligament is Y shaped and helps with knee stability
What radiological sign is seen in osteopetrosis ?
Bone within a bone - densely sclerotic bone
Which conditions can cause calcium pyrophosphate deposition?
Hemochromatosis, hyperparathyroidism, hypophosphatasia
What is the hallmark of gout ?
Marginated erosions with overhanging margins
What is the ultrasound sign for gout ?
Double contour sign - irregular hyperechoic line of urate crystals deposited on the hyperechoic cartilage
Where does gouty tophi like to develop ?
Olecranon bursa of the elbow
What is Calcific Tendinopathy ?
Deposition of calcium hydroxyapatite in tendons which are degenerating or hypoxia
What is the most common site of Calcific Tendinopathy ?
Shoulder
In the wrist which tendon is mostly affected by calcium hydroxyapatite deposits ?
Flexor carpi ulnaris tendon
What is Milwaukee shoulder ?
Intraarticular deposition of calcium hydroxyapatite, resulting in rapid destruction of the shoulder joint - including the rotator cuff and glenohumeral joint.
what percentage of patients with haemachromatotis develop arthropahty ?
50%
which organs are in the reticuloendothelial system ?
Spleen , liver suffer cells and bone marrow
what radiological sing in the hand might be present in haemochromatosis ?
hook like osteophytes at the MCP - can involve all of them
what happens to the joint space in early acromegaly?
widened joint space
what hand features suggest acromegaly ?
spade like tuffs
beak like osteophytes of the metacarpal heads
who is at risk of amyloid arthroapthy ?
patients on chronic hemodialysis - with chronic renal failure
what is the shoulder pad sign and what arthropathy is it associated with ?
predominance of the anterior deltoid - seen in amyloid athropathy
a patient with intervertebral disc calcification at ever level with mild disc loss height has what ?
ochronosis / alkaptonuria
if there is bilateral ankle arthorsis and erythema nodosum - what should you be worried about ?
sarcoidosis
what hand features might be seen in sarcoid?
lace like lytic lesions in the middle or distal phalanx
MSK - what does haemophilia tend to affect.
knees, elbows , ankles
what is the characteristic features of haemophilia in the elbow?
enlarged radial head and widened trochlear notch
in juvenile idiopathic arthritis, where might ankylosis occur ?
in the cervical spine or the wrist
what is the differential for ankylosis of the cervical spine ?
juvenile idiopathic arthritis and klippel-feil syndrome
what is klippel feil syndrome ?
failure of cervical segmentation
what is the most common cause of shoulder neuropathic athropathy ?
syringomyelia
What are the three most common cause of Charcot joint ?
- Diabetes
- Syringomeylia
- Leprosy
Which arthritis cause demineralisation ?
HORSE
Haemophilia
Osteomalacia
Rheumatoid and Reuters
Slceroderma
SLE
Which arthritis doesn’t cause demineralisation ?
PONGS
Psoriatic
Osteomyelitis
Neurogenic
Gout
Sarcoidosis
What joint is most commonly affected in SAPHO ?
Sternoclavicular joint
What does SAPHO stand for ?
Synovitis
Acne
Palmoplantar pustulitis
Hyperostosis
Osteoiditis
What is Gardner syndrome ?
Osteomas
Intestinal polyps
Soft tissue desmoid tumours
Where doe osteomas arise from ?
The bony cortex
Where do bone islands arise from ?
The medullary canal
What is the classic appearance seen in melorheostosis
Candle wax appearance - irregular sclerosis of the bony cortex- usually affected by a single sclerotome
What sign on nuclear medicine is seen with an osteoid osteoma ?
Double density sign
Where does osteosarcoma tend to metastasise to ?
The lungs
What are the 4 main subtypes of osteosarcoma ?
- Periosteal - inner periosteum
- Paraosteal - outer periosteum
- Telangectatic osteosarcoma
- Conventional
What is the most common subtype of osteosarcoma ?
Conventional 75%
What is the classic feature of paraosteal osteosarcoma?
A type of osteosarcoma that arises from the outer layer of the periosteum.
Cauliflower outgrowths
What is olliers syndrome ?
Multiple enchondromas
What is maffucis syndrome ?
Multiple enchondromas and vascular malformations results in phleboliths
In the pelvic bones, what does fibrous dysplasia look like ?
Cystic lesions