Cardiac Flashcards
how can ‘stress’ be initiated in a myocardial perfusion study
physical - treadmill
pharmacologic-adrenergic (dobutamine)
pharmacologic - vasodilatory (adenosine, dipyridamole, regadenoson)
what is the gold standard for evaluating cardiac viability ?
F-18 FDG PET
how does thallium perfusion study work to investigate myocardial perfusion
thallium is only taken up in viable myocardial tissue, therefore during stress - if the tissue is ischaemic it won’t be taken up, but during rest it will revascularise and be taken up again .
when would you use a pharmacological stress ?
patients who can’t exercise, left bundle branch block
how does dipridamole work ?
caused endogenous adenosine to acculumate - this cause vasodilation of the coronary arteries - therefore if a coronary artery has critical stenosis, it won’t be able to relax and therefore have relative perfusion
what must be held before dipyridamole is given ?
caffeine and theophylline
what is the reversal agent to dipyridamole and adenosine ?
aminophylline
when is a vasodilator contraindicated ?
COPD, severe asthma, recent caffeine ?
what would you give if a vasodilator is contraindicated ?
dobutamine ( B-agonist that increases myocardial oxygen demand)
what does myocardial stunning indicate and what is it ?
significant obstructive coronary artery disease
Myocardial stunning is when an acute transient myocardial ischaemic event results in a prolonged wall motion abnormality which eventually resolves.
how can you assess motion artefact on a cardiac study ?
sinogram - will show horizontal lines at the areas of movement
what is hibernating myocardium :
viable but hypo perfused myocardium due to severe chronic schema, which may benefit from revascularization
what is stunned myocardium
delayed recovery of contractile function despite reperfusion after a transient ischaemic insult
what is the gold standard for evaluating myocardial viability and hibernation /
FDG - PET
what is the FDG Pet uptake known as in a hibernating myocardium ?
Increased - mismatch
Low perfusion and normal/increased metabolism
what is amyloidosis ?
extracellular deposition of insoluble proteins
what does left atrial enlargement and cardiomegaly indicate with regards to cardiac valve disease
mitral regurgitation
what does left atrial enlargement and a normal sized heart indicate ?
mitral stenosis
what does enlarged aorta and cardiomegaly indicate ?
aortic regurgitation
what does an enlarged aorta and normal sized heart indicate ?
aortic stenosis
what does the double density sign represent ? q
enlarged left atrium
what is a coronary artery CT angiogram the first line test for ?
patients with acute chest pain, in low to intermediate risk pateitns without known CAD - with normal cardiac enzymes and non-ischemic egg
what is the luminal diameter of a coronary artery ?
3mm
if a coronary artery arises from the pulmonary artery is it benign or malignant ?
malignant
which coronary artery courses are malignant ?
inter arterial course - between the aorta and pulmonary artery
intramural course - within the aortic wall
what is myocardial bridging ?
band of myocardium overlying a segment of a coronary artery most commonly seen in the mid or distal LAD
what is the agatston score ?
the total calcium In the coronary tree
what reporting classification is used to standardised cardiac reports ?
CAD-RADS
If there is a coronary artery stenosis of 25-49% what is recommended ?
preventative therapy
if there is a cadres 70-100% what is recommended ?
function tests, invasive coronary angiography and consider revascularisation
what sings indicate a high risk plaque (increased risk of ACS)
low attenuation (<30)
Spotty calcification
Napkin ring (Low attenuation core and higher outer ring)
Postive remodeeling
what are the main complication following coronary artery stenting ?
stent thrombosis and in-stent restenosis
what is the preferred diagnostic modality to assess coronary bypass grafts ?
cardiac catherterisation
what are the two most common causes of coronary artery dilatation ?
atherscerlosis and Kawasaki disease
In cardiac MRI what is the spin echo sequence used for?
high spatial resolution but slow to obtain - good for anatomy