Movement of Molecules Flashcards

(52 cards)

1
Q

What % of body weight is water for males and females?

A

60% males

55% females

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2
Q

What % of fluids are intracellular fluid and extracellular fluid?

A

2/3 intracellular fluid

1/3 extracellular fluid

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3
Q

What % of extracellular fluid is interstitual fluid and plasma?

A

80% extracellular fluid

20% plasma

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4
Q

Order composition of fluids from largest to smallest

A
  1. 2/3 of body weight is fluids
  2. 60% of ICF
  3. 80% is interstitual fluid
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5
Q

What is a solute?

A

anything that is dissolved in a solvent

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6
Q

What is a solvent?

A

anything that dissolves other substances

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7
Q

What are electrolytes?

A

charged ions that dissociate in water (break up)

eg. sodium, pottasiumm

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8
Q

What are some examples of non-electrolytes?

A

Glucose, lipids, urea

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9
Q

What are 2 passive processes?

A

diffusion and ozmosis

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10
Q

What is an example of a primary active process?

A

sodium-pottasium pump

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11
Q

What is an example of secondary active transport?

A

symporters and anti-porters (indirectly uses ATP)

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12
Q

What is an example of vesicular active transport?

A

endocytosis and exocytosis

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13
Q

What is the chemical sign for pottasium and sodium?

A

Pottasium - K+

Sodium - Na+

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14
Q

Is there higher or lower concentration of sodium found outside the cells?

A

Higher

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15
Q

How many sodium ions are moved out of the cell for every potassium ions moved in?

A

3 sodium out, for 2 potassium in

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16
Q

What is the difference between an antiporter and a symporter?

A

Antiporter - can move molecule in different direction

Symporter - can move molecule in same direction

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17
Q

What is bulk phase endocytosis?

A

cell drinking, tiny droplets of ECF are engulfed

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18
Q

What does an acid do?

A

releases/donates hydrogen ions when in a solution

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19
Q

What does a base do?

A

accepts/removes hydrogen ions from a solution

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20
Q

What is an example of a base and an acid?

A

Base - bicarbonate ion

Acid - hydrochloric acid

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21
Q

What is acidosis?

A

excess hydrogen ions in the body (pH has dropped)

22
Q

What does BAD stand for?

A

“Bases accept, acids donate?

23
Q

On a pH scale what does below 7 indicate?

A

acidic, lots of hydrogen ions

24
Q

On a pH scale what does above 7 indicate?

A

basic (alkaline), less hydrogen ions

25
What determines how acidic/basic a solution is?
the concentration of free hydrogen ions in the body
26
What is the plasma fluid pH?
7.35 - 7.45
27
What is the function of a buffer system?
a solution that will resist changes in pH when a strong acid/base is added, to maintain pH within narrow limit Either: - bind to extra free H+ ions - release more free H+ ions
28
What is an example of a chemical buffer?
Bicarbonate system
29
What is the chemical equation of the bicarbonate system?
carbonate acid -> bicarbonate ion + hydrogen
30
What is a ligand?
chemical that binds to something
31
What is a ligand-gated channel?
needs ligand to open
32
What is a mechanically gated channel?
closed until mechanical stimulus | deformation of cell, heat, pressure
33
What is a voltage-gated channel?
closed until voltage alters the electrical charge of cell
34
What is a leakage channel?
Always open, ions move down their concentration gradien
35
What are some factors that influence rate of diffusion?
- steepness of concentration gradient - temperature - mass of substance - surface area - distance
36
What is simple diffusion?
passive process where substances can move freely through the lipid bi-layer of the plasma membrane with the help of protein channels or carriers eg. gases, non-polar hydrophobic substance, small. molecules
37
What is facilitated diffusion?
passive process where molecules that are too polar or highly charged, move through the bilayer of the plasma membrane via a channel or carrier protein 2 types: - channel-mediated facilitated diffusion - carrier-mediated facilitated diffuion
38
What are the 2 types of diffusion?
simple and facilitated
39
What is ozmosis?
the movement of water across the plasma membrane from a high concentration of water, to a low concentration of water
40
What is hydrostatic pressure?
water's weight forcing it back
41
What is osmotic pressure?
the amount of pressure needing to restore to the starting condition
42
What is tonicity?
The ability of solution to change the shape of a cell (because of the movement of water)
43
What is osmolarity?
the number of solute particles in a solution
44
What is hypertonic solution?
relatively high concentration of non-permeable solutes outside of the cell - creation (cell shrinks)
45
What is hypotonic solution?
relatively low concentration of non-permeable solutes outside of the cell - lysis (cell bursts)
46
What is an isotonic solution
equal concentration of non-permeable solutes in the ICF and ECF  (no net movement of water)
47
What does resting membrane potential mean?
a cell's difference in charge between outside and inside areas, at resting state
48
What are some factors that affect RMP?
- uneven distribution of ions across cell membrane - difference in leak channels - more potassium leak channels than sodium
49
Is the inside of cell positive or negative at resting state
Negative
50
What is the RMP?
-70mV
51
Do electrolytes or non-electrolytes dissociate in water?
Electrolytes
52
Explain the process of sodium-potassium ATPase
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