motor neuron degeneratin Flashcards
motor neuron disease
inherited or acquired
upper, lower or mixed
LMN diseases
poliomyelitis
amyotrophic lateral sclerosis
gullian barre
HIv AIDS
myasthenia gravis
immune response attacks NM junciton
can be treated
will affect strength and respirate mm
motor unit diseases
myasthenia gravis , duchenne
duchnen muscular
x linked recessive, survival >20 yrs
myotonic dystrophic
Guillain barre
rare rapid autoimmune disorder attacking myelin sheath of PNS
cause of Gillian barre
unknown but often preceded by infectious illness
first symptoms of Guillain barre
weakness / tingling extremities leading to paralysis of body
T/F guillian barre might need ventilator
yes
cure for Guillain barre
no but high dose immunoglobulin therapies can lessen severity
Gillian barre prognosis
varied
better outcome <40
many experience chronic pain /fatigue
might take weeks to years to recover
poliomyelitis
caused by viral infection
destruction of anterior horn (LMN)
leads to mm weakness
is poliomyelitis U or LMN
LMN
do ppl recover from polio
many recover
cure for polio?
no cure but prevented through vaccination
post polio syndrome
25-40% of individual who suffered an acute attack of poliomyelitis
symptoms appear 15-30yrs after original disease
slow progression
ALS cause
unknowns
ALS presentation
progressive, fatal disrupts signals to all mm
ALS u or L MN
both
UMN / LMN signs ALS
first seen in arms hands, legs and swallowing
equal bilateral mm weakness
progress
spasticity , brisk reflexes
is sensation bladder or ocular mm spared in ALS
yes
prognosis of ALS
relentless progression of signs / symptoms
average survival 2-5yrs, 5-10 if ventilated
incidences ALS
40-60 yr old, more men
ALS stages
1-6
whats PT do for ALS 1
educate, pain , gnerela conditions
whats PT do for ALS 2
maintain strength, respect fatigue
PROM
movement
orthotics
whats PT do for ALS3
w/c
prevent complications
education
maximize indp
whats PT do for ALS 4
education for independence
whats PT do for ALS5
decrease emphasis on strength
emphasis on caregiver education (ROM, position, respiration)
whats PT do for ALS 6
comfort, psych support
parkinsons presentation
progressive CNS motor / non motor UMN
cardinal signs of parkinsons
righty
bradykinesia
tremor
is there postural instability in parkinsons
later stages yes
prognosis of parkinsons
progressive w long subclinical period
variable rate of progression
PT management parkinsons
meds CV fitness postur external cues internal cues momentum
MS
autoimmune disease of CNS
cause MS
unknown
where is damage in MS
targeted to myeline sheath causing inflammation / interruption of nerve impulses
T/F MS is progressive and irreversible
true
types of MS
progressive relapsing
seconding progressive
primary progressive
relapsing remitting
incidence of MS
high in Canada
1/340
UMN sign diseases
Parkinsons and MS
LMN sign diseases
Guillain barre
Polio
mixed UMN/LMN
ALS
how to intervene with degenerative dieseas
be sensitive to health prognosis
be aware of progression
PT management of later chronic deteriorating neurological conditions is similar to __
early stage manger of acute recovering Neuro conditoin
PT management of early stage chronic deteriorating neuro condition is
later stage management of acute recovering neuro condition
LMN lesion face
paralysis of ipsilateral upper and lower face
can’t raise eye brow or smile on affected side
UMN lesion face
paralysis of contralateral lower face
can’t smile on affected side but can raise eye brow
Bells Palsy
LMN
stroke
UMN
complete peripheral nerve lesion recovery treatment
recovery not possible
treatment : range, circulation , mouth care eye care
incomplete peripheral nerve lesion recovery treatment
possible
same as complete but add mm retraining
goal symmetry
upper motor neuro lesion recovery treatment
recovery can not be predicted
incorporate treatment from complete / incomplete peripheral nerve lesions