Most common 2 Flashcards
LS
MC site of schwannomas
skin and subcutaneous tissues (outside CNS)
MCC of unilateral sensorineural hearing loss
vestibulochochlear schwannoma
MCC of multiple enhancing CNs
mets
MC cerebellopontine cistern mass
vestibular schwannoma
MC of all Meckel cave tumors
schwannomas
MC jugular foramen schwannoma but still rare
glossopharyngeal schwannomas (IX)
MC site of facial nerve schwannomas
geniculate fossa
MC of the pure motor nerve shwannomas but rare
oculomotor (III)
MC location of CN III schwannoma
interpeduncular cistern (2nd mc: cavernous sinus)
MC reported sites of intraparenchymal schwannomas
frontal and temporal lobes
Scalp and orbital plexiform neurofibromas most commonly involve what nerve?
V1 (ophthalmic)
Most commonly affected CNs in malignant peripheral nerve sheath tumors
vestibular, facial, and trigeminal
MC site of distant extracranial mets in malignant peripheral nerve sheath tumors
lung
MC type of (CNS) lymphomas / Vast majority of primary CNS lymphomas / Approximately 80% of secondary CNS lymphomas
diffuse large B-cell lymphoma
Preferred site of primary CNS lymphomas
cerebral hemispheres - deep-seated w/ predilection for periventricular WM, esp the corpus callosum (next mc: basal ganglia and thalami)
MCC of a solitary ring-enhancing lesion in an HIV/AIDS patient
lymphoma
MC involved site in lymphomatoid granulomatosis
lung > skin
MC manifestation of LCH / MC overall manifestationf of LCH
bone lesions / skin and bone lesions
MC presenting symptom of CNS LCH
central diabetes insipidus
MC presentation of CNS LCH
craniofacial involvement
MC manifestations of LCH on NECT
one or more sharply marginated lytic skull or facial bone defects
Most commonly affected sites in LCH
craniofacial bones and skull base (followed by hypothalamic-pituitary region)
MC sites of LCH-related neurodegenerative lesions
brainstem and/or cerebellum (bilaterally symmetrical confluent T2/FLAIR typically in dentate nuclei)
MC site of punctate foci of parenchymal enhancement in LCH
pons
MC form of childhood cancer / MC malignancy in children
leukemia (ALL (80%) > AML)
Solitary bone plasmacytomas/solitary plasmacytomas are most commonly found in the?
vertebrae and skull
Solitary bone plasmacytomas occur most frequently in the?
spine > skull - always red marrow
MC primary bone malignancy
multiple myeloma
Most sensitive imaging modality for detecting diffuse and focal bony lesions
whole-body MR
MC etiologies/MC underlying causes of extramedullary hematopoiesis
anemias (thalassemia, SCD, hereditary spherocytosis) > myelofibrosis/myelodysplastic syndromes
MC site of extramedullary hematopoiesis
axial skeleton
MC head and neck sites of extramedullary hematopoiesis
face and skull
MC intracranial location of extramedullary hematopoiesis
subdural space
Pathologic hyperplasia most commonly occurs in response to?
end-organ failure
MCC of pathologic pituitary hyperplasia
primary hypothyroidism -> TSH cell hyperplasia
MC physiologic form of pituitary hyperplasia / MC etiology of pituitary hyperplasia
diffuse PRL cell hyerplasia (during preg and lactation) / PRL cell hyperplasia
MC abnormality in children w/ isolated growth hormone deficiency
hypoplastic pituitary gland (pag multiple - stalk abnormalities)
MC suprasellar mass in children / MC suprasellar mass in the pediatric population
craniopharyngioma (2nd MC: optic pathway/hypothalamic pilocytic astrocytoma)
MC nonglial neoplasm in children
craniopharyngioma
MC nonneuroepithelial intracranial neoplasm in children
craniopharyngioma
MC site of ectopic pituitary adenomas
sphenoid sinus
2 MC pituitary adenomas
prolactinomas and GH-secreting tumors
MC extracranial sources of mets to the stalk and/or pituitary gland
lung and breast
MC type of hypophysitis
lymphocytic hypophysitis (MC in pregnant and postpartum females - difficult to distinguish from physiologic PRL cell hyperplasia; if (+) stalk enlargement - hypophysitis > hyperplasia)
MC site of sarcoidosis
hilar lymph nodes
MC type of sphenoid pneumatization
sellar
5 MC overall suprasellar masses / big 5
macroadenoma, meningioma, aneurysm, craniopharyngioma, and astrocytoma
MC calvarial site of fibrous dysplasia
frontal bone
MC sites of FD in the face
orbit, zygoma, maxilla, and mandible
2nd MC pediatric primary skull lesion (after dermoid cysts)
fibrous dysplasia
Most exaggerated example of abnormal osseous remodeling
Padet disease
Most commonly affected CN in Paget disease
CN VIII
MC overall aneurysmal bone cyst location
metaphysis of long bones 70-80% (vertebrae, generally posterior elements 15%)
2nd mc pathologically proven bone tumor of childhood
aneurysmal bone cyst
MC site of chordomas
sacrum > sphenooccipital (clival) region > spine
Most helpful feature in the classification of intracranial cysts
location
MC scalp mass in children
Langerhans cell histiocytosis
3 statistically mc scalp cysts
epidermoid, trichilemmal, and dermoid
MC type of extraaxial cyst / MC off-midline extraaxial supratentorial cyst / 2nd MC cystic-appearing extraaxial mass in the CPA cistern (after epidermoid) / MC of all congenital intracranial cysts / MC nonneoplastic intracranial cyst
arachnoid cyst
Nearly 2/3 of arachnoid cysts are found in the?
middle cranial fossa, anteromedial to the temporal lobe (next mc: cerebral convexity, pred over frontal lobes 15%)
MC supratentorial midline location for arachnoid cysts (although relatively rare)
suprasellar cistern > quadrigeminal cistern and velum interpositum
MC location of arachnoid cysts in the posterior fossa
CPA cistern > retrocerebellar
Best sequences to distinguish cystic-appearing intracranual masses from one another
FLAIR and DWI
MC intracranial developmental cyst / 3rd mc CPA mass (after vestibular schwannoma and meningioma) / MC cystic mass in the CPA
epidermoid cyst
Single mc site of epidermoid cysts
CPA cistern - nearly half (other locations: middle cranial fossa (sylvian fissure) and parasellar region - 10-15%)
MC site of dermoid cysts
suprasellar cistern > posterior fossa and frontonasal region
MC location of intracranial neurenteric cysts
midline posterior fossa (anterior to the pontomedullary junction)
MC CNS site of neurenteric cysts
spine > skull - always red marrow
MC parenchymal cysts
prominent perivascular spaces > hippocampal sulcus remnants
MC nonneoplastic parenchymal brain “cysts”
perivascular spaces
Perivascular spaces have striking predilection for?
inferior 3rd of basal ganglia, esp near anterior commissure
MC site of neuroglial cysts
frontal lobe (supratentorial) (adj to but no communication w/ ventricles)
MC location of choroid plexus cysts
atrium of the lateral ventricle (within the choroid plexus glomus)
MC of all intracranial cysts
choroid plexus cysts
MC “lesion” that mimics a colloid cyst on MR
pulsatile CSF flow
MC location of ependymal cysts
atrium of the lateral ventricles
Largest and most prominent of the deep GM nuclei
thalami
MC bilateral basal ganglia lesions
normal variants, such as physiologic calcification and prominent perivascular spaces
MCC of abnormality in the bilateral basal ganglia
vascular, hypoxic-schemic insults, common metab disorders, such as chronic liver failure
MC lesion to affect the putamen
hypertensive hemorrhage
Part of basal ganglia most sensitive to hypoxia
globus pallidus
Most commonly affected locations in Wernicke encephalopathy
mammillary bodies, hypothalamus, medial thalamic nuclei (adj to 3rd ventricle), tectal plate, and periaqueductal GM
MCC of Wernicke encephalopathy
alcohol use disorder
Most characteristic imaging feature of methanol poisoning
bilateral basal ganglia
Most commonly abused opioid
heroin
MC acute complication of injected heroin
stroke (inhaled - leukoencephalopathy)
MC secondary complication of heroin abuse
infection - endocarditis
Radiation-induced vascular malformations are most commonly seen in?
children who have recevied whole-brain RT for ALL
Single most important risk factor for developing a new primary CNS neoplasm
radiotherapy (70% meningiomas, 20% malignant astrocytomas or medulloblastomas)
2 mc abnormalities in chemotherapy-assoc acute toxic CNS injury
PRES and treatment-induced leukoencephalopathy
MC single protein or enzyme deficiency disease to present in childhood
X-linked adrenoleukodystrophy
MC inborn error of amino acid metabolism
phenylketonuria
2nd mc inherited disorder of amino acid metabolism
nonketotic hyperglycinemia
MC type of neurodegeneration w/ brain iron accumulation (NBIA)
PKAN - panthothenate kinase-associated neurodegeneration
MC manifestation of acute hypertensive encephalopathy
PRES
MC overall cause of PRES
preeclampsia
MC imaging pattern of PRES
dominant parieto-occipital pattern
MC overall condition predisposing to malignant hypertension
essential hypertension
2nd mc manifestation of chronic hypertensive enceph (after WM lesions)
microhemorrhages
MC location of hypertensive microhemorrhages
basal ganglia
Childhood hypoglycemic enceph is most commonly associated w/ ?
type 1 DM
MCC of transient (neonatal/infantile) hypoglycemia
maternal diabetes
MCC of severe, persistent (neonatal/infantile) hypoglycemia
congenital hyperinsulinemia
MC imaging abnormality in patients w/ acute DKA
vasogenic cerebral edema
MC location for an ectopic thyroid
central tongue base
MC findings in the brain in primary hyperparathyroidism
basal ganglia calcifications on NECT
MCC of secondary HPTH
chronic renal disease
MC progressive compressive CN involvement/neuropathy in secondary hyperparathyroidism due to renal osteodystrophy
optic neuropathy
Most commonly associated condition / MCC of cytotoxic lesions of the corpus callosum
use and subsequent withdrawal of antiepileptic drugs
Iron accumulation is greatest in the?
pars reticulata of the substantia nigra
MC site of obstructing membranes
foramina of Luschka
MC mass found at the foramen of Monro
colloid cyst
MC tumor that causes intraventricular obstructive hydrocephalus in children
medulloblastoma
MC general imaging feature of normal pressure hydroceph
ventriculosulcal disproportion
Spontaneous intracranial CSF leaks are most commonly associated with
arachnoid granulations in the lateral sphenoid sinus
Largest and deepest of all cranial fossae
posterior fossa
MC type of Chiari malformation
Chiari 1
MC of all congenital brain malformations / MC CNS malformation / Single mc malformation that accompanies other developmental brain anomalies and syndrome
anomalies of the cerebral commissures (especially the corpos callosum) / corpus callosum dysgenesis
MC congenital cerebellar malformation
Dandy-Walker malformation
MC presentation of DWM
increased ICP sec to hydrocephalus
MC brain morphologic defects in fetal alcohol syndrome
CC agenesis and regional increases in cortical thickness
MC inherited cause of mental retardation in boys
fragile X syndrome
MC causes of secondary microcephaly
ischemia, infection, maternal diabetes, and trauma
MC and mildest form of primary microcephaly
microcephaly with simplified gyral pattern (MSG)
MC type of focal cortical dysplasia
Type IIb
Single mcc of severe early-onset drug-resistant epilepsy in children and young adults
focal cortical dysplasias
MC form of cortical malformation in adults
periventricular nodular heterotopia (PVNH)
MC associated abnormality w/ PVNH
ventriculomegaly
Mildest form of classic licencephaly
subcortical band heteroptopia / double cortex syndrome
MC location of polymicrogyria
bilateral perisylvian
MC imaging abnormality in infants with CMV infection / MC malformation of cortical development associated with CMV infection
polymicrogyria (more common than calcification)
Most severe end of the holoprosencephaly continuum
aprosencephaly and atelencephaly (AP/AT) - rare
Most severe form of holoprosencephaly
alobar
MC form of holoprosencephaly
alobar > semilobar > lobar > unclassifiable
MC human forebrain malformation / Only malformation in which the posterior corpus callosum forms while the anterior aspects are absent
holoprosencephaly
Most developed and least anomalous form of HPE
lobar
MC CNS tumor predisposition syndromes
neurofibromatoses
MC CNS neoplasm in NF1 / MC glioma in NF1
pilocytic astrocytoma
MC site of NF1 pilocytic astrocytomas
optic pathway
MC site of plexiform neurofibromas
orbit
MC sites of meningiomas in NF2
falx and cerebral convexities
2nd MC inherited tumor syndrome (after NF1)
tuberous sclerosis complex
MC site of subependymal nodules in tuberous sclerosis complex
along the caudothalamic groove
MC site of hemangioblastomas
dorsal half of the cerebellum (2nd: medulla)
MC site of supratentorial hemangioblastomas
pituitary stalk
MC location of leptomeningial angioma in Sturge-Weber
parietooccipital
MC site of extracutaneous hemangiomas
subglottis
MC location of atretic cephalocele (contains just dura, fibrous tissue, and degenerated brain tissue)
obelion (sagittal suture at the level of the parietal foramina)
MC type of cephalocele in European/North America Caucasians / MC type of cephalocele among Caucasians
occipital
MC location of congenital cephalocele
squamous portion of occipital bone
MC type of cephalocele in SEA
frontoethmoidal
MC type of cephalocele among Australian aborigines, Malaysians, and select Southeast Asian groups
sincipital (sabi ni Osborn synonymous ang frontoethmoidal at sincipital)
MC of the 3 subtypes of frontoethmoidal cephaloceles
frontonasal > nasoethmoidal > nasoorbital
MC single-suture craniosynostosis / MC nonsyndromic craniosynostosis
sagittal/scaphocephaly > coronal > metopic > lambdoid
Rarest type of nonsyndromic craniosynostoses
lambdoid
MC syndromic craniosynostosis
bilateral coronal
MC of all soft tissue tumors
ordinary lipoma
MC overall site of intracranial lipomas
interhemispheric fissure (supratentorial, mostly in or near midline)
MC posterior fossa site of intracranial lipomas
CPA cistern
Prob the MCC of marrow reconversion seen on MRI
incidental finding in women who are obese (and who are often smokers)
MC tendon abnormalities seen on MRI
degeneration, tenosynovitis, and tears
Most commonly affected tendon in xanthomas
Achilles tendon and extensor tendons of the hand
MC injuries in sports
muscle strains
Fascial herniation of muscle is most commonly seen where?
anterior lower leg or thigh
Most commonly involved in (diabetic) muscle ischemia
thigh, especially the vastus musculature (80%); next is the calf (20%)
Site most commonly involved in fibrolipomatous hamartoma
hand, especially the median nerve
Most commonly affected by ganglion cysts
peroneal nerve at the knee
MC location of pain and numbness because of Morton’s neuromas
2nd and 3rd web spaces
MC locations for Morton’s neuroma
2nd and 3rd intermetatarsal spaces
MC sites of involvement of Brodie’s abscess (or subacute osteomyelitis?)
tibia and femur
Most specific sign of active chronic osteomyelitis
sequestrum (best shown w/ CT)
MC causative agent of pyomyositis
S. aureus
MC sites of involvement of neuroathropathy (diabetes)
Lisfranc joints, Chopart joints (talonavicular and calcaneocuboid joints), and subtalar joints
MC tumor-like entities that originate in joints and may manifest as a swollen joint
synovial chondromatosis and PVNS
MC site of loose bodies
knee
MC location of intraosseous lipoma
calcaneus, proximal femur, and humerus
MC benign tumor of bone
osteochondroma
MC mechanism of injury that results in a complete tear of the ACL
twisting force combined with a valgus stress
MC mechanism of ACL injury
forced valgus in external rotation
Site that is most vulnerable to injuries from excessive tensile forces
musculotendinous junction
MC site of avulsion fractures
pelvis
MC avulsion fracture in upper limb
medial epicondyle apophysis (common flexor/pronator tendon) in children
MCC of insufficiency fractures
osteoporosis
MC site of transient osteoporosis
hips
MC site of spontaneous osteonecrosis of the knee
weight-bearing surface of the medial femoral condyle
MC site of osteochondritis dissecans
knee, ankle, elbow
MC site of osteochondritis dissecans in the knee
lateral aspect of the medial femoral condyle along its non-weight-bearing surface
MC location of partial-thickness tears of the supraspinatus tendon
undersurface/articular aspect (rather than superior/bursal surface)
MC partial-thickness tear / MC cuff tear of all kinds
rim rent tear - insertional fibers of the cuff on the greater tuberosity are disrupted from the bone / PASSTA or PASTA lesions - partial supraspinatus tendon avulsion; can occur either anteriorly on greater tuberosity involving supraspinatus or posteriorly on greater tuberosity involving infraspinatus
Abnormalities in posterosuperior impingement most commonly affects the?
supraspinatus tendon, posterosuperior labrum, and humeral head where the greater tuberosity abuts the posteriosuperior glenoid during abduction and ER
After rotator cuff disease, the major abnormality that affects the shoulder
instability
Most variable of the 3 glenohumeral ligaments / Most variable in morphology of all the anterior glenohumeral capsular ligaments
middle
Most important of the glenohumeral ligaments for anterior and posterior joint stabilization
inferior
Glenohumeral ligament most frequently affected with instability
inferior
Largest and most important of the glenohumeral ligaments
IGHL or IGL
MC of all glenohumeral joint instabilities
anterior instability, particularly that prooduced by lesions of the IGHL-labral complex
Primary restraint to anterior translation of the humeral head at 90 deg of abduction
anterior band of the IGHL
MC labral shapes
triangular > round > flat > absent
Bennett lesion is most commonly seen in?
pitchers
MC injury after anterior dislocation of the glenohumeral joint
Bankart lesion