More glutamate Flashcards
1
Q
NMDA has ____ subunits
A
7
2
Q
Binding spots on NMDA
A
2 for glycine
2 for glutamate
3
Q
NMDA allows entry of
A
Ca++
K+
Na+
4
Q
Depolarization which pushes Mg++ out of pore
A
-40mV
5
Q
Necessary for Mg++ binding
A
Asparagine (four residues bind Mg++)
6
Q
Co-agonist of NMDA
A
glycine
7
Q
In order to get NMDA contribution,
A
repetitive stimulation (LTP) is needed
8
Q
Current after stimulation compared with AMPA
A
…
9
Q
NMDA I,V graph
A
…
