Metabotropic glutamate receptor Flashcards

1
Q

metabotropic glutamate receptors tend to be located

A

edge of postsynaptic mebrane

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2
Q

First two steps of cascade

A

G protein

Phospholipase C

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3
Q

Middle steps of cascade

A

PIP2
DAG
Protein kinase C

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4
Q

Finals steps of cascade

A

Calmodulin
CaMKII
AMPA phosphorylation

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5
Q

Phosphorylation of AMPA receptors causes them

A

to open more frequently and longer

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6
Q

PLC also does this

A

affects IP3, raising intracellular Ca++, activating calmodulin (CaM)

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7
Q

diagram

A

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