Metabotropic glutamate receptor Flashcards
1
Q
metabotropic glutamate receptors tend to be located
A
edge of postsynaptic mebrane
2
Q
First two steps of cascade
A
G protein
Phospholipase C
3
Q
Middle steps of cascade
A
PIP2
DAG
Protein kinase C
4
Q
Finals steps of cascade
A
Calmodulin
CaMKII
AMPA phosphorylation
5
Q
Phosphorylation of AMPA receptors causes them
A
to open more frequently and longer
6
Q
PLC also does this
A
affects IP3, raising intracellular Ca++, activating calmodulin (CaM)
7
Q
diagram
A
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