dec1pt2 Flashcards
taste receptor sodium channel candidate
amiloride sensitive sodium channel
taste receptor proton channel candidate
complex formed by PKD113 and TRP
umami,sweet, and bitter use this type of mechanism
GPCR
receptor type for bitter
T2
receptor type for umami and sweet
T1
Types of T1
T1R1, T1R2, T1R3
T1 receptors form
heterodimers
taste receptor cells either generate AP or
rely on calcium influx through TRPM5 for NT release without AP
few types of
sweet receptors, just need to know energy source
same G protein
umami and sweet
bitter G protein
gustducin
cells expressing T1R2 do not express
T1R1
knockout T1R1 and firing rate of what is abolished
umami gustatory nerves
knockout T1R3 abolishes
umami and sweet
abolishes sweet
knockout T1R2
no evidence these form heterodimers
T1R1 and T1R2
if you put a sweet receptor in a bitter taste cell animals will
avoid sweet
animal experiemnt supports
labled line theory
miarculin works by
binding T1R2T1R3 complex and activating it at pH change
T receptors parcing
