dec1pt2 Flashcards

1
Q

taste receptor sodium channel candidate

A

amiloride sensitive sodium channel

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2
Q

taste receptor proton channel candidate

A

complex formed by PKD113 and TRP

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3
Q

umami,sweet, and bitter use this type of mechanism

A

GPCR

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4
Q

receptor type for bitter

A

T2

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5
Q

receptor type for umami and sweet

A

T1

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6
Q

Types of T1

A

T1R1, T1R2, T1R3

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7
Q

T1 receptors form

A

heterodimers

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8
Q

taste receptor cells either generate AP or

A

rely on calcium influx through TRPM5 for NT release without AP

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9
Q

few types of

A

sweet receptors, just need to know energy source

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10
Q

same G protein

A

umami and sweet

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11
Q

bitter G protein

A

gustducin

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12
Q

cells expressing T1R2 do not express

A

T1R1

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13
Q

knockout T1R1 and firing rate of what is abolished

A

umami gustatory nerves

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14
Q

knockout T1R3 abolishes

A

umami and sweet

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15
Q

abolishes sweet

A

knockout T1R2

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16
Q

no evidence these form heterodimers

A

T1R1 and T1R2

17
Q

if you put a sweet receptor in a bitter taste cell animals will

A

avoid sweet

18
Q

animal experiemnt supports

A

labled line theory

19
Q

miarculin works by

A

binding T1R2T1R3 complex and activating it at pH change

20
Q

T receptors parcing

A