mood disorders reading notes Flashcards
anhedonia
loss of energy and inability to find pleasure
low positive affect, normal positive affect
Mixed features
term for experiencing depressive symptoms during a manic or hypomanic phase, or manic during depressive episode
lifetime course of major depressive
gonna relapse
4-7 mior lifetime episodes on average each lasting 4-5 months
first episode tends to be longest
double depression
severe mood dis typified by major depression episodes superimposed over background of dysthmia disorder
integrated grief
a stage of grieving at which the finality of death and meaning of life is acknowledged and appreciated
complicated grief
a reaction to loss characterised by persistent, intense grief and persistent distracting ot impairing concerns about the consequences or circumstances of the loss
after 6 months/ 1 year chances of recovering from severe grief = considerably reduced and normal process becomes a disorder
why grief should maybe be its own dis
strong yearning = activation of dopamine
this is in contrast with depression
depression incidence from kids to adults
children gender is equal
at puberty takes off in girls (most evident in severe depression)
different presentations at different ages
dangerous is depressed as a child = poor outcomes, have to try treat
what do we mean by probound
prevalence in first degree relatives
eg rates in relatives of probounds with mood dis 2/3 times greater than of controls
bipolar in the proband
increased risk of some mood dis = supports bipolar may be a severe variant of mood dis rather than fundamental different dis
genetic effects of mood dis felt strongest in ..
women
low levels of what neurotransmitter implicated in mood dis
serotonin
mood swings
again permisive hypothesis
stress hypothesis
overactivity of the HPA axis which produces stress hormones
neurohormones
hormones that affect the brain
increasingly being studied and their link to psychopathology
eg cortisol is elevated in depressed patients
these hormones could be harmful to neurons
hippocampus and mood dis
low volume implicated
ect produce neurogenesis in the hippocampus
also animal exercise has been shown to increase volume