Mood Disorders Flashcards
What are the two categories of mood disorders
Bipolar Disorders and Unipolar Disorders
Common symptoms of depressive disorders
- Dysphoria
- Anhedonia
- Psychomotor retardation
- Psychomotor agitation
- Fatigue
- Worthlessness/Guilt
- Trouble Concentrating
- Changes in sleep and appetite
- sometimes psychotic symptoms
Dysphoria
Intense feelings of sadness
Anhedonia
Having no interest in things one previously found pleasure in
Psychomotor retardation
Physically slowed appearance
Psychomotor Agitation
Physical agitation
- fidgeting, difficulty sitting still
Major Depressive Episode
Period of two or more weeks marked by at least 5 symptoms including sad mood and/or loss of pleasure
Major Depressive Episode
Presence of at least one episode
- Can’t have history of mania or a shift in life that can explain mood
- once you experience one episode you are more likely to experience more
- Episode on average lasts 2 weeks to 9 months (will resolve on own)
Prolonged Greif Disorder
Impairment for more than 6 months pertaining to greif
Prevalence of MDD
Estimated 10% across cultures
- More common in woman than men across all cultures
- Less common in people of color
MDD with seasonal pattern
- Two years of experiencing and fully recovering from episodes
- For most, starts in fall/winter and resolves in spring
- Cannot be explained by psychosocial events, such as seasonal unemployment
Persistent Depressive Disorder
- Depressed mood for most of the day, most days, for at least 2 years
- Less intense symptoms
- Symptoms do not cease for more than 2 months at a time
- Worse functional consequences than MDD (more commonly comorbid with anxiety and substance use disorder)
Biological Approach to theories of depression
Heritability
- Females: 36-44%
- Males: 18-24%
Monoamines
- Serotonin, norepinephrine, dopamine
- Less about how much of each and more about the interaction between them
Brain Differences
- Neural plasticity: ability for nervous system to modify itself in response to experience and injury
- Differences in anterior cingulate, prefrontal cortex, amygdala, hippocampus
Differences in prefrontal cortex with depression
Decreased grey matter
- Specifically on left side
Differences in Amygdala with depression
Increase in size and activity
Differences in Hippocampus with depression
Decrease in size and activity