Molybdenum Flashcards
Where is soil geographically rich in molybdenum?
Florida
California
Oregon
Nevada
What are sources of excess molybdenum?
Soil, plants, industrial contamination, molybdenum containing fertilizers,
or if there is a copper deficiency
T/F: Molybdenum plays a role in the formation of uric acid
true
Excess molybdenum will cause a copper _____
deficiency
Low molybdenum will cause a copper ________
accumulation
What species are the most susceptible to molybdenum toxicosis?
Cattle
can also be seen in sheep
What animals are resistant to molybdenum toxicosis?
Horses and pigs
High levels of _____ will increase the toxicity of molybdenum
Sulfate
Dietary ______ decreases molybdenum toxicity
Copper
What is the maximum tolerable dietary level of molybdenum?
5-10 ppm
T/F: Molybdenum can be excreted in toxic levels in cows milk
TRUE
Where is molydenum absorbed?
GIT
What is the MOA of molydenum tox?
Copper deficiency
Copper is essential for hematopoeisis, CT metabolism, myelin formation in newborns, pigmentation, and bone formation
Cu plays a role in cytochrome oxidase and aromatic amino acid metabolism
What clinical signs will be seen in a cow with molybdenum toxicosis?
Severe dhr (greenish, with fluid and gas bubbles) 8-10 days following exposure
Rough hair coat, depigmentation of hair around the eyes
wt. loss, anemia, osteoporosis, exostosis, lameness, pica
decreased libido and infertility
What are diagnostic levels of molybdenum in the blood, and liver?
Elevated molybdenum: blood (> 0.1ppm) Liver (> 5 ppm)
Decreased copper in the blood and liver
Decreased cytochrome oxidase activity
