Molecular: Ferguson Flashcards
T/F: Inheritance patterns are based on changes in the genetic sequence.
False, based on changes in the packaging, not the genetic sequence
What does a Code Reader Complex do?
Reads the histone code
T/F: Histone code is unchangeable.
False, changes as the cell needs
Why is having more copies of a gene better?
Less need for few mutations
What is the term for a duplicated gene that has been irreversibly inactivated by multiple mutations.
Pseudogene
What are the 4 major proteins at a replication fork?
DNA polymeraseDNA primaseDNA helicasessDNA binding protein
What does DNA helicase do?
Unwinds parent strand of DNA
What does DNA polymerase do and what are its two components?
Synthesizes the new DNA strand.Loading clamp and sliding clamp
What does DNA primase do?
Creates starting points for DNA synthesis from parent strand
What does ssDNA binding protein do?
Binds to ssDNA to prevent parent strands from joining back together
What are the 3 DNA repair pathways?
Base excisionNucleotide excisionHomologous recombination
What type of junctions does homologous recombination create?
Holliday junctions
T/F: Gene conversion is the more common form of homologous recombination than crossing over.
True
When do homologous and sister chromatids separate during meiosis?
Homologous: Meiosis ISister: Meiosis II
What can produce genetic variation by inducing spontaneous mutations and can insert anywhere in the genome?
Transposons