Epidemiology Flashcards
What type of randomization has multiple randomizations into 2 or more groups, which are then subdivided into more groups?
Factorial Randomization
What type of randomization has multiple randomizations, but the subjects must stay in their assigned group; no switching
Parallel Randomization
What type of randomization has groups serve as their own controls by switching from one intervention to another during the study?
Crossing-over Randomization
What is single-blind blinding?
Subjects don’t know,Researchers do know
What is double-blind blinding?
No one knows
What is open-label blinding?
Everyone knows
What is placebo therapy (dummy therapy)?
Fake treatment made to look like real treatment
What is double-dummy therapy?
Where there is more than 1 placebo used
What is the placebo effect?
Improvement in condition by power of suggestion
What is the hawthorne effect?
Patients are eager to please the researchers
What is a run-in/lead-in phase?
All patients given placebo to establish baseline/standardization
What type of randomization has 1 randomization into 2 or more groups and is used to test a single hypothesis?
Simple Randomization
What type of study is observational, analytical, and allows researchers to be passive observers of natural events occurring in naturally exposed & un-exposed groups?
Cohort study
What is a cohort?
A group with something in common
What is known in a cohort study? (disease or exposure)
Exposure (rows of 2x2 table)