Module 9 Flashcards
What are the parts of the endocrine system?
Endocrine organs
Components of other organs
Diffuse endocrine system
What controls the pituitary? What does it control?
Hypothalamus
Controls the activity of other glands
What are the parts of the pituitary gland?
Anterior/adenohypophysis- secretes tropic and direct action hormones
Posterior/hypophysis/pars nervosa- stores vasopressin/ADH and oxytocin
How are secretory cells of the anterior pituitary gland categorized?
Colour of stain- chromophils vs chromophobes
Hormone content
What anterior pituitary cells are there and what do they contain?
Somatotrophs- GH
Mammotrophs- prolactin
Gonadotrophs- LH and FSH
Corticotrophs- ACTH, lipotropin, endorphins
Thyrotrophs- TSH
What is the function of the thyroid?
Produces hormones that regulate basal metabolic rate (T3 and T4)
Produces calcitonin- parafollicular C cells lower blood calcium
What is the functional unit of the thyroid?
Follicle
Single layer of cuboidal epithelium
Lumen filled with colloid- thyroglobulin, stores T3 and T4
Flat/cuboidal when inactive but become tall columnar when active
What is the function of the parathyroid?
Secretes PTH, raises serum calcium levels
What cells are in the parathyroid, what are their functions?
Chief cells- secrete PTH, acts on bones, kidneys and intestines
Oxyphil cells- inactive
What are the areas of the adrenal glands?
Outer cortex- corticosteroids
Inner medulla- secretes catecholamines
What are the zones of the adrenal cortex?
Zona glomerulosa- outer layer of secretory cells, aldosterone
Zona fasciculata- long rows separated by capillaries, cortisol
Zona reticularis- inner layer of irregularly arranged cells, androgens and glucocorticoids
What are the secretory units of the endocrine pancreas?
Islets of Langerhans
What are the cells of the islets of Langerhans and what do they secrete?
Beta- insulin and amylin
Alpha- glucagon
Delta- somatostatin
PP/F cells- pancreatic polypeptide
Where is the diffuse neuroendocrine system located? What is its function?
GI and respiratory tracts
Regulate tract activity with the ANS
What chemicals can act as hormones?
Steroids
Peptides
Proteins
Amines