Module 8

Question 1

The fermentation of glucose in blood to produce ethanol can be prevented by:

Answer 1

Sodium fluoride

Question 2

Fatal poisoning due to methanol is usually a result of:

Answer 2

Production of formic acid

Question 3

In isopropyl alcohol intoxication the following is found as a metabolite:

Answer 3

Acetone

Question 4

Methanol, Ethanol and Isopropanol. Rank in order from most toxic to least toxic.

Answer 4

Methanol, Isopropanol, Ethanol

Question 5

Ethylene glycol is metabolized by alcohol dehydrogenase to:

Answer 5

Glycoaldehyde

Question 6

Antidote for ethylene glycol poisoning:

Answer 6

Fomepizole

Question 7

These crystals are associated with ethylene glycol poisoning:

Answer 7

Calcium oxalate

Question 8

Methanol is primarily metabolized via alcohol dehydrogenase to:

Answer 8

Formaldehyde

Question 9

Ethanol metabolites include:

Answer 9

Ethyl glucuronide and ethyl sulfate

Question 10

The generally accepted values for Vd for men and women are ____ and _____, respectively.

Answer 10

0.68 L/kg and 0.55 L/kg

Question 11

One treatment for methanol intoxication is to give the patient excessive amounts of:

Answer 11

Ethanol

Question 12

Stages of alcohol influence with the blood alcohol concentration range

Answer 12

• 0.01 – 0.05 = subclinical
  
  • 0.03 – 0.12 = euphoria
  • 0.09 – 0.25 = excitement
  • 0.18 – 0.30 = confusion
  • 0.25 – 0.40 = stupor
  • 0.35 – 0.50 = coma
  • 0.45+ = death

Question 13

What are the 3 stages of ethylene glycol toxicity?

Answer 13

Neurologic, Cardiopulmonary, Renal stages