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MH701 Psychopharmacology > module 7 - pediatric > Flashcards

module 7 - pediatric Flashcards

1
Q

schedule of psychostimulants

A

Schedule II

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2
Q

Method of action for methylphenidate (Concerta, Ritalin)

A

Inhibits reuptake of dopamine and norepinephrine in the prefrontal cortex

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3
Q

method of action of amphetamine (Adderall)

Dextroamphetamine (Dexedrine)

A

Inhibits reuptake of dopamine and norepinephrine in multiple brain regions including dorsal and ventral striatum, substantia nigra, and regions of the cortex

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4
Q

presenting the options and asking the family to choose one

A

authoritative

most recommended

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5
Q

being more directive with family regarding which option they should choose

A

authoritarian

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6
Q

half life of amphetamine and dextroamphetamine

A

6 hours

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7
Q

half life of mehtylphenidate (Ritalin)

A

4-5 hours

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8
Q

Peaks in 3 hours and is prescribed BID

A

Dexmethylphenidate (Focalin)

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9
Q

prodrug activated by lysine resulting in gradual release

A

Vyvanse (lisdexamfetamine)

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10
Q

First-line treatment of ADHD

A

methylphenidate (Ritalin)

Dextroamphetamine

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11
Q

provides 6 hours of benefit and prevents dosing at school

A

mehthylphenidate (Ritalin)

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12
Q

twice as potent and provides 6-8 hours of benefit

A

dextroamphetamine

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13
Q

adverse effects of ritalin and adderrall

A

anorexia/weight loss, HR/BP/Cardiac hx, dysphornia, moodiness, insomnia, dizziness, irritability, rebound phenomena

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14
Q

Nonstimulant drugs for ADHD

A

Strattera (atomexetine)

Wellbutrin (Bupropion)

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15
Q

MOA of Strattera

A

norepinephrine reuptake inhibitor

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16
Q

MOA of Bupropion

A

Norepinephrine and dopamine reuptake inhibitor

17
Q

liver metabolism

kidney metabolism

A

Greater in kids than adults = clear drugs faster

18
Q

protein binding in children

A

kids have less protein binding=

more drug availability

19
Q

Risk of TD may be greater in kids

A

true

20
Q

First-line medications for depression in children and adolescents

A

fluoxetine (Prozac)
citalopram (Celexa)
sertraline (Zoloft)

21
Q

FDA approved for adolescent depression

A

Lexapro (escitalopram)

Prozac (fluoxetine)

22
Q

Evidenced-based treatments for childhood anxiety

A

Fluoxetine (Prozac)
sertraline (Zoloft)
Paroxetine (Paxil)

23
Q

FDA approved for OCD in children and adolescence

A

Sertraline (age 6+)
Fluoxetine (age 7+)
Fluvoxamine (age 8+)
Clomipramine (age 10+) - NOT first line- TCA

24
Q

Recommended first-line treatment for manic episodes in adolescents (13+)

A

aripiprazole (abilify) up to 12 weeks

25
Q

Alpha-adrenergic agonists to help with inattentiveness, irritability, tic disorders

A

Cloinidine (Catapres)

Guanfacine (Tenex)

MH701 Psychopharmacology (19 decks)

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