antidepressants - Video lectures Flashcards

1
Q

A drug that binds to a specific receptor producing an effect identical to that usually produced by the neurotransmitter

A

Full agonist

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2
Q

Examples of full agnoists

A

morphine, methadone, oxycodone, hydrocodone, heroin, codeine, fentanyl

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3
Q

A compound that binds to a receptor that blocks or reduces the action of another substance at the receptor site

A

Antagonist

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4
Q

examples of antagonists

A

flumazenil (blocks benzodiazepine at GABA)

Schizophrenia drugs block dopamine 2 receptors

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5
Q

slightly sedating
increases appetite
increases both NE and Serotonin

A

Mirtazapine

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6
Q

Alpha2 antagonist often combined with SSRI or venlafaxine

A

mirtazapine

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7
Q

Increases NE and DA

does not work on serotonin

A

bupropion (Wellbutrin)

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8
Q

Can be used in patients with ADHD and depression

A

bupropion (Wellbutrin)

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9
Q

Cocaine detox
combat SSRI sexual side effects
smoking cessation

A

bupropion (Wellbutrin)

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10
Q

weak SSRI that does not have sexual side effects and can be used first line for insomnia

A

Trazodone

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11
Q

Serious side effect of priapism

A

Trazodone

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12
Q

Highest risk of drug-to-drug interactions

A

fluoxetine (Prozac)
fluvoxamine (Luvox)
paroxetine (Paxil)
sertraline (Zoloft)

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13
Q

when to switch to a different SSRI

A

after 4-8 weeks of first failed trial

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14
Q

when to switch to a different drug class

A

after two SSRIs have failed

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15
Q

consider for patients with anxiety disorders along with depression

A

Paxil (paroxetine)
Venlafaxine (Effexor)
Duloxetine (cymbalta)

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16
Q

SSRIs most energizing to most sedating

A
Prozac
Zoloft
Celexa
Lexapro
Paxil
17
Q

makes you sleepy and fat

A

Paxil

18
Q

Energizing and weight neutral

A

Prozac

Wellbutrin

19
Q

may cause weight loss

A

Venlafaxine (effexor)

20
Q

Most likely to cause diarrhea

A

zoloft

21
Q

Most likely to cause nausea and vomiting

A

Prozac
Effexor
Cymbalta