Modul 3, part 2 Flashcards

1
Q

Cardiovascular responses to fear

A

Increased atherosclerosis, increased cardiac ischemia, increased BP, decreased heart rate variability, increased MI, sudden death

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2
Q

cardiovascular pathway of fear in brain

A

amygdala to locus coeruleus

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3
Q

Memories are stored in what area of the brain?

A

hippocampus

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4
Q

Loop in the brain associated with worry and obsessions

A

cortico-striato-thalamo-cortical circuit

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5
Q

Reduces actions of benzos

benzo antagonist

A

flumazenil

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6
Q

agonist for GABAa receptors

Enhances GABA effects

A

benzodiazepines

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7
Q

targets GABAa receptors

A
Benzodiazepines
Sedatives
hypnotics
barbituates
alcohol
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8
Q

5HT1A partial agonist used to treat anxiety

A

Buspirone (Buspar)

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9
Q

Anxiolytic that takes weeks to take effect , like SSRIs

A

Buspirone (Buspar)

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10
Q

works on serotonin on both postsynaptic and presynaptic areas

A

buspar

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11
Q

excess norepinephrine symptoms

A

fear/panic

tremor, sweating, tachycardia, hyperarousal

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12
Q

reduced stimulation of beta adrenergic receptors leads to. ____

A

decreased anxiety and associated symptoms

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13
Q

Nonbenzodiazepine agonists

A

zolpidem (Ambien)
Zaleplon (Sonata)
eszopiclone (Lunesta)

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14
Q

Rapid-acting benzos

A

Valium
Ativan
Xanax

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15
Q

shorter half life but slower onset of action

A

lorazepam

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16
Q

longer half life but produce more rapid but briefer action

A

Diazepam

17
Q

benzodiazepines used for insomnia (no more than 7-10 days) without thorough investigation of cause of insomnia

A

temazepam, flurazepam, triazolam

Sole purpose is insomnia