Modul 3, part 2 Flashcards
Cardiovascular responses to fear
Increased atherosclerosis, increased cardiac ischemia, increased BP, decreased heart rate variability, increased MI, sudden death
cardiovascular pathway of fear in brain
amygdala to locus coeruleus
Memories are stored in what area of the brain?
hippocampus
Loop in the brain associated with worry and obsessions
cortico-striato-thalamo-cortical circuit
Reduces actions of benzos
benzo antagonist
flumazenil
agonist for GABAa receptors
Enhances GABA effects
benzodiazepines
targets GABAa receptors
Benzodiazepines Sedatives hypnotics barbituates alcohol
5HT1A partial agonist used to treat anxiety
Buspirone (Buspar)
Anxiolytic that takes weeks to take effect , like SSRIs
Buspirone (Buspar)
works on serotonin on both postsynaptic and presynaptic areas
buspar
excess norepinephrine symptoms
fear/panic
tremor, sweating, tachycardia, hyperarousal
reduced stimulation of beta adrenergic receptors leads to. ____
decreased anxiety and associated symptoms
Nonbenzodiazepine agonists
zolpidem (Ambien)
Zaleplon (Sonata)
eszopiclone (Lunesta)
Rapid-acting benzos
Valium
Ativan
Xanax
shorter half life but slower onset of action
lorazepam