module 6 part 2 Flashcards
Thiamine deficiency leading to decrease mental functioning, paralysis, ataxia, nystagmus, confusion
Can lead to death
Wernicke’s encephalopathy (acute)
Thiamine deficiency characterized by targeting the limbic system with severe memory problems, confabulation, disorientation, gait disturbances, neuropathy
Korsakoff syndrome (chronic)
CNS stimulants
amphetamines/meth
caffeine
nicotine
club drugs
Ecstasy (MDMA)
stimulant and hallucinogens
opioid partial agonist
buprenorphine
opioid antagonist
naloxone (narcan)
naltrexone
short-acting opioid antagonist
naloxone (narcan)
long-acting opioid antagonist
naltrexone (Vivitrol - IM injection)
can cause immediate withdrawal symptoms in patient currently on opioids
buprenorphrine
buprenorphine combined with naloxone
suboxone
prevents misuse of medication by crushing and injecting.
poorly absorbed via sublingual route
naloxone
patients must be in mild withdrawal state prior to starting
suboxone (buprenorphine/naloxone)
Most effective in highly dependent patients
methadone
mu opioid receptor agonist that blocks effects of opioids while suppressing withdrawal symptoms
methadone
given at treatment centers once daily
40-60 mg daily usually
methadone
Vivitrol injection (long-acting = every 4 weeks)
Naltrexone
patients should be opioid free fro 7-10 days before initiating treatment
naltrexone
decreases cravings
prevents people from drinking but does not prevent withdrawal symptoms
begin treatment on the 5th day of abstinence
acamprosate
side effects of acamprosate
diarrhea, upset stomach, appetite loss, anxiety, dizziness, difficulty sleeping
tabs taken 3 times daily
acamprosate
Side effects of disulfiram
nausea, headache, vomiting, chest pain, difficulty breathing
MOA of Adderall
blocks NET and DET
Transported into DA terminal
FDA approved for aggression in children and adolescents
Risperdal
FDA approved for pediatric depression
Fluoxetine (prozac)
FDA approved for OCD in children
zoloft (sertraline)
Luvox (fluvoxamine)
prozac
clomipramine
most appropriate for depression in elderly
desipramine (Norpramin)
nortryptline (pamelar)
least likely to cause drug to drug interactions in elderly
venlafaxine (Effexor)