module 4 mood disorders Flashcards

1
Q

Manic episodes with or without psychosis and/or major depression

A

Bipolar 1

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2
Q

Hypomanic episode with major depression; no history of manic or mixed episode

A

Bipolar 2

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3
Q

hypomanic and depressive symptoms that do not meet criteria for bipolar 2 disorder; no major depressive episodes

A

cyclothymia

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4
Q

Does not meet criteria for MDD, Bipolar 1 or 2, or cyclothymia

A

Bipolar disorder not otherwise specified

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5
Q

Add to mood stabilizer during manic episode

A

antipsychotic

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6
Q

Do not give antidepressants in patients with bipolar

A

True

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7
Q

Lithium level therapeutic index

A

0.5-1.5 mEq/L

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8
Q

Signs of lithium toxicity

A

Movement (Tremor)
Nephrotoxicity
HypOthyroidism
Pregnancy problems

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9
Q

Labs to monitor with lithium

A
Lithium level
electrolytes
creatinine and BUN
CBC
TSH/thyroid panel
Pregnancy test
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10
Q

Inhibits voltage-gated sodium channels

Increases GABA

A
Valproic Acid (Depakote)
Carbamazepine (Tegretol)
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11
Q

contraindicated in pregnancy

Decreases folate

A

Depakote (Valproic Acid)

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12
Q

Side Effect of fatal hepatic necrosis

A

Depakote

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13
Q

Risk of agranulocytosis

A

Carbamazepine (Tegretol)

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14
Q

Inhibits sodium channels but does not effect GABA

A

Lamictal (lamotrigine)

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15
Q

Better for use in patients with mood disorders without mania because it does not increase GABA

A

Lamictal

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16
Q

Side effect of Lamictal

A

Rash

Can progress to Steven Johnson Syndrome

17
Q

Off-label anticonvulsant sometimes used for mood stabilization

A

topiramate (Topamax)

18
Q

Enhance GABA by increasing frequency of opening GABA receptors

A

Benzodiazepines

19
Q

Enhance GABA by increasing the duration of opening of GABA receptors

A

Barbituates

20
Q

short-acting benzos

1-12 hour half life

A

Triazolam
Oxazepam
Midazolam

21
Q

Medium-acting benzos

12-40 hour half life

A

Clonazepam
Alprazolam
Lorazepam
Temazepam

22
Q

Long-acting benzos

40+ hour half life

A

Diazepam (Valium)

Chlordiazepoxide (Librium)