module 4.2 Flashcards
purpose of the respiratory system
transfer O2 from environment to RBC
transfer CO2 from blood to air
regular acid base balance
what is asthma
variable airflow obstruction caused by bronchospasm
4 types of asthma
eosinophilic
paucigranuolytic
neutrophilic
mixed granulocytic
yearly asthma triggers
air pollution
allergens e.g. dust mites , pollen
exercise
viral infection
cigarettes
what is pollen
male gametes of conifers and flowering plants
what are mast cells
granule filled cells
when activated degranulation occurs and histamine and cytosines are released
what does histamine do
causes localised edema, dilation of blood vessels, heat, redness and itchiness
why do we have mast cells
protective roles against bacteria, virus, parasites
host defence/ immune surveillance
2 reasons allergies are increasing
hygiene - less exposure to pathogens
microbiota - immune system not used to old microbiota
5 features of useful medicine
effective
convenient
well tolerated
safe
cheap
how do medicines act in the body
bind to receptor proteins
can act as agonist or antagonist
what do agonists do
stimulate the receptor
what do antagonists do
bind to but do not stimulate the receptor
