module 4 final review Flashcards

1
Q

genes that are involved in sex determination

A

1) FOXI2: drives development of ovaries
2) SOX9: produces anti-mullerian hormone
3) STAT-3: roles in temp/stress to determine sex determination

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2
Q

testosterone effects before & after birth

A

before: descent of testes & masculinizes reproductive tract
after: growth & maturation of reproductive system, and spermatogenesis

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3
Q

3 steps to spermatogenesis

A

1) mitotic proliferation
2) meiosis
2) spermiogenesis

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4
Q

sertoli cell function (5)

A

1) nourish sperm with lactate
2) eat cytoplasm
3) destroy defective germ cells
4) secrete tubule fluid
5) produce androgen binding protein

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5
Q

androgen binding protein

A

binds testosterone so levels are high around sperm to drive spermatogenesis

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6
Q

ejaculation pathway

A

efferent ducts -> epididymis -> ductus deferns -> ejaculatory duct -> urethra

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7
Q

seminal vesicle secretions

A

1) fructose- sperm energy
2) prostaglandins= smooth muscle contraction
3) fibrinogen = forms clots

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8
Q

prostate gland function

A

1) secrete alkaline fluid to neutralize acidic vaginal secretions
2) clotting enzyme = reduce semen loss
3) prostate-specific antigen release

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9
Q

prostate specific antigen

A

breaks down seminal clot to sperm can move to oocyte

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10
Q

sexual arousal

A

1) arterioles dilate
2) erectile tissue fills with blood
3) erection = venous outflow decreases for penetration

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11
Q

erection reflex

A

spinal reflex in PNS is triggered by mechanoreceptors in glans pens
- mediated by nitric oxide
- inhibits SNS so ensure arterioles are closed

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12
Q

what do mechanoreceptors do in erection

A

1) stimulate sacral region & inhibits SNS
2) promotes PNS = vasodilation
3) increased blood flow to penis

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13
Q

male resolution

A

1) pathway gets sensitized - only lasts for short period
2) SNS begins to take control again
3) slower blood flow into penis = decrease erection
4) returns to pre-arousal state

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14
Q

3 types of AI techniques

A

1) conventional- semen injected into cervix with corkscrew pipette
2) tubular extension-semen into uterus
3) 2 prong approach- double insemination into uterine horn & cervix

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15
Q

increase in testosterone causes

A

decrease in LH secretion

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16
Q

increase in GnRH causes

A

increase in LH

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17
Q

increase in LH causes

A

increase in leydig cells = increase in testosterone

18
Q

increase in FSH causes

A

spermatogenesis & inhibin

19
Q

increase of inhibin

A

decrease FSH

20
Q

fertilization steps

A

1) sperm penetrates cumulus cells
2) sperm head binds to zona pellucida- previtelline interacts with ZPS receptors
3) acrosomal reaction-breakdown ZP with digestive enzymes
4) sperm penetrates ZP
5) sperm fuses with ovum membrane
6) calcium deposition blocks binding of other sperm

21
Q

6 female reproduction functions

A

1) oogenesis
2) sperm reception
3) fertilization
4) nourishment of fetus
5) parturition
6) lactation

22
Q

seasonal breeding pathway

A

1) retina sense light
2) neurons relay light info to hypothalamus
3) pineal gland produces melatonin & kisspeptin
4) anterior pituitary releases GnRH= ovulation & estrus

23
Q

oviparous

A

offspring develops in egg externally

24
Q

ovoiviparous

A

internal fertilization, egg shell is put on externally

25
viviparous
offspring develops in mother - uses placenta
26
3 oviduct functions
1) captures ova 2) internal fertilization site 3) deposition of albumen
27
2 uterus functions
1) protect fetus 2) calcification of eggs
28
ovarian/follicular phase
oocyte is developing & getting ready to be ovulated, estrogen is dominant
29
uterine/luteal phase
after egg is released, progesterone is dominant
30
5 placenta secretions
1) progesterone 2) estrogen 3) relaxin 4) chorionic gonadotropin 5) placental lactogen
31
follicular wave
multiple waves of follicular development that occur each cycle - ovulation only occurs with LH surge
32
what causes a LH surge
increase in progesterone
33
2 things LH surge does
triggers ovulation & stops estrogen synthesis
34
3 things progesterone does in placenta
1) prevents endometrium from contracting 2) prevents cycling 3) forms mucous plug
35
3 parturition steps
1) cervical softening - relaxin & PGF-2a release 2) rhythmic contractions - gap junctions & oxytocin receptors formed 3) placenta explusion - CRH release = increase ATCH, cortisol & DHEA -progesterone -> estrogen
36
estrous cycle phases
1) proestrus-developement of follicles - decrease progesterone & increase estrogen 2) estrus: period of sexual receptivity - decrease progesterone & increase estrogen 3) metestrus- development of corpus luteum - increase progesterone & decrease estrogen 4) diestrus - increase progesterone & decrease estrogen until corpus luteum decreases
37
labour feedback loop
placenta, CRH, fetal ant pit, ACTH, fetal adrenal cortex, cortisol or DHEA
38
female: pre-puberty vs puberty
pre- no effect of surge center puberty-no effect of tonic center
39
male: pre-puberty vs puberty
pre-oestradiol/testosterone inhibition puberty-no inhibition of testosterone/oestradiol
40
what cells do LH & FSH act on
LH- leydig cells = increase testosterone FSH= sertoli cells = spermatogenesis & inhibin