endocrine pathways Flashcards

1
Q

thyroid hormone secretion

A

hypothalamus, TRH, anterior pituitary, TSH, thyroid gland, TH, target cells, circulation, BMR & body temp effects

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2
Q

growth hormone secretion

A

hypothalamus, GnRH / GHIH -> anterior pit -> GH -> adipose, muscle, iver -> IGF-1

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3
Q

stress comand pathway

A

stress -> hypothalamus -> CRH -> ant pit -> ATCH -> adrenal cortex -> cortisol -> most cells -> metabolic changes

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4
Q

calcitonin/PTH pathway

A

low plasma Ca -> PTH -> increase PTH -> increase plasma Ca

high plasma Ca -> thyroid cells -> increase calcitonin -> decrease plasma Ca

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5
Q

osteoblast pathway

A

osteoblasts -> RANK ligand or OPG

RANK ligand -> macrophages -> increase osteoclast action -> decrease bone mass

OPG -> rank ligand bound to OPG -> blocks RANK action -> decreased osteoclast action -> increased bone mass

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