Module 3 Lecture 21 Flashcards
The Public/Population Health Model
Provide the maximum benefit for the largest number of people at the same time reducing inequities in the distribution of health and well being
Individual vs Population Health Care
Individual: Clinicians genereally deal with individuals as they aim to treat disease to restore health (Reactive)
Population: concerned with the health of groups of individuals, in the context of their environment (comprehensive, proactive approach)
Epidemiology determines the ______ or ______ between a given ______ and _______ in populations so appropriate _______ ______ can be taken
relationship or association; exposure and dis-ease; preventive measures
Bradford Hill Criteria (every criteria doesn’t have to be filled)
Temporality, Strength of Association, Consistency of Association, Biological Gradient (dose-response), Biological plausibility of association, specificity of association and reversibility
Temporality
First the cause then the disease (essential to establish a causal relationship) e.g. smoking causes lung cancer
Strength of Association
The stronger the association, the more likely to be causal in absence of known biases e.g. British Drs study: RR>10
Consistency of Association
Replication of findings by different investigators, at different times, in different places, with different methods proving it is less likely due to chance e.g. multiple studies showing similar results
Biological Gradient (dose-response)
Incremental change in disease rates in conjunction with corresponding changes in exposure
Biological plausibility of association
Does the association make sense biologically? e.g. chemicals in tobacco that are known to promote cancers (carcinogens)
Specificity of association
A cause leads to a single effect. However, a single cause often leads to multiple effect e.g. smoking leads to multiple outcomes
Reversibility
The demonstration that under controlled conditions changing the exposure causes a change in the outcome
Cause of a disease
An event, condition, characteristic or combination of these factors which play an essential role in producing the disease
A Sufficient cause…
is a factor/s that will inevitably produce the specific disease
A Component cause…
is a factor that contributes towards dis-ease causation, but is not sufficient to cause dis-ease on it’s own
A Necessary cause…
is a factor (or component cause) that must be present if a specific dis-ease is to occur