Module 2: Epithelial Transport Flashcards
What is epithelial transport
movement of substances across two plasma membranes, one entering the cell and one leaving the cell
What is a lumen
The hollow opening in the center
What is absorption
transport of materials into the internal environment from the external environment
What is secretion
transport of materials from the internal environment to the external environment
What is the apical side
the side that faces the lumen, or inwards
What is the basolateral side
the side that faces the blood/interstitial fluid, or outwards
How do substances move through the epithelial cell
brought into the cell through the apical membrane and they are transported out of the cell through the basolateral membrane
Sodium transport
Concentration of sodium is greater in the lumen of the small intestine than in the epithelial cells that line the small intestines, so the sodium naturally wants to move down its concentration gradient, enters through apical membrane and pumped out at the basolateral membrane
Water transport
When the body needs to absorb water, epithelial cells actively pump solutes from the basolateral membrane of the cell into the ISF via aquaporins
Glucose transport
the concentration of glucose is smaller in the lumen than in the epithelial cells, so glucose has to be actively transported into the cell at the apical surface - once the glucose is inside of the cell it has to exit the cell and enter the interstitial fluid by crossing the basolateral membrane