Module 1 - Congenital & Genetic Disorders/stres Flashcards
Inherited disorders may be caused by
Single gene expression
chromosomal defect
Polygenic expression
What are single-gene disorders?
- Trait controlled by one set of alleles
- Transmitted to subsequent generations
Chromosomal anomalies are usually caused by an error during
Meiosis
What are teratogenic agents?
Agents that cause damage during embryonic or fetal development
In recessive disorder’s, how can a child be affected?
Both parents must pass on the defective gene to produce an affected (homozygous) child
if a child is heterozygous (one normal gene and one disease gene are present in the pair), then that child is
Is the carrier and shows no clinical signs of disease
What are autosomal dominant disorders?
The presence of the defect in only one of the alleles produces clinical expression of the disease