Mod 1 antimalarials Flashcards
generic name
chloroquine
(drugs with -quine suffix)
contraindicated in…
patients w/ retinal or visual field changes
use cautiously in…
patients with severe GI, neuro, blood d/o, hepatic dz, alcoholism, G6PD deficiency
G6PD
helps RBC work, protects them from harmful substances
therapeutic effects
prevention of malaria
improvement of acute malaria
4wks after leaving area
SE/AE
changes in vision and hearing
monitor for…
renal dysfx
overdose leading to toxic sx
(headache, drowsiness, visual disturbances, N/V, cardiovasc collapse, shock, convulsions)
MOA
attacks parasite during asexual phase
primaquine special MOA
can kill parasite in both phases
multi-drug therapy
antimalarials may be used together or with sulfonamide
prophylactic therapy
before travelling to effected area and for 8 weeks after leaving