Mod 1 antimalarials Flashcards

1
Q

generic name

A

chloroquine
(drugs with -quine suffix)

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2
Q

contraindicated in…

A

patients w/ retinal or visual field changes

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3
Q

use cautiously in…

A

patients with severe GI, neuro, blood d/o, hepatic dz, alcoholism, G6PD deficiency

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4
Q

G6PD

A

helps RBC work, protects them from harmful substances

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5
Q

therapeutic effects

A

prevention of malaria
improvement of acute malaria
4wks after leaving area

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6
Q

SE/AE

A

changes in vision and hearing

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7
Q

monitor for…

A

renal dysfx
overdose leading to toxic sx
(headache, drowsiness, visual disturbances, N/V, cardiovasc collapse, shock, convulsions)

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8
Q

MOA

A

attacks parasite during asexual phase

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9
Q

primaquine special MOA

A

can kill parasite in both phases

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10
Q

multi-drug therapy

A

antimalarials may be used together or with sulfonamide

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11
Q

prophylactic therapy

A

before travelling to effected area and for 8 weeks after leaving

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