MOD 1 antihelmintic Flashcards

1
Q

major parasitic helminths

A

roundworms (nematoda)
flatworms (platyhelminthesis)

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2
Q

MOA

A

(1)preventing microtubule formation
compromising glucose uptake
(2)blocking neuronal transmission causing starvation, paralysis, death
(3)inhibit ATP formation, impair Ca uptake causing paralysis and death

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3
Q

prolonged therapy considerations

A

can result in liver damage and bone marrow suppression

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4
Q

generic drug

A

mebendazole

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5
Q

mebendazole contraindication

A

pregnancy

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