Mixed Acting Sympathomimetics

Question 1

What are the two mixed acting sympathomimetics?

Answer 1

1) Ephedrine
2) Pseudoephedrine

Question 2

What effect does ephedrine have on blood pressure?

Answer 2

Increase

Question 3

___ is a mixed-acting sympathomimetic that is a direct a1 agonist (minimal direct b2 agonist activity)

Answer 3

Pseudoephedrine

Question 4

___ is both a direct and indirect sympathomimetic that enhances NE release from sympathetic neurons. Also: it is an alpha/beta adrenergic receptor agonist

Answer 4

Ephedrine

Question 5

How does Ephedrine affect HR/CO? Peripheral resistance?

Answer 5

Increases all

Question 6

How does Ephedrine affect the bladder?

Answer 6

Increase resistance to urine outflow

Question 7

How does Ephedrine affect respiration?

Answer 7

Bronchodilation

Question 8

True or False: Ephedrine has potent effects on the CNS

Answer 8

True

Question 9

Adverse effects of ephedrine (2) ?

Answer 9

1) insomnia
2) hypertension
-increased risk if you have pre-existing heart conditions

Question 10

What was ephedrine previously used for?

Answer 10

Asthma

Question 11

Clinical use for pseudoephedrine?

Answer 11

Nasal decongestant