Ganglionic Agent

Question 1

___ is a stimulant and inhibitor

Answer 1

Nicotine

Question 2

Mecamylamine is only an ___

Answer 2

inhibitor

Question 3

Both nicotine and mecamylamine act on ___ receptors

Answer 3

Nicotinic receptors

Question 4

At __ doses, nicotine receptor agonists inhibit receptor and surrounding membrane leading to ___ and persistent depolarization

Answer 4

desensitization

Question 5

Three site of nicotine action?

Answer 5

1) CNS
2) Cardiovascular and GI
-autonomic ganglia
3) Skeletal Muscle
-NM junctions

Question 6

Hypotension, bradycardia, coma, and respiratory failure are features of the __ phase of nicotine poisoning

Answer 6

depressor

Question 7

____ is a type of nicotine poisoning that can occur while handling tobacco

Answer 7

Green Tobacco Sickness

Question 8

GI symptoms, hypotensive fainting, and respiratory paralysis are features of ____ _____

Answer 8

nicotine poisoning

Question 9

____ agents, such as ___, are the first effective therapy for treatment of hypertension

Answer 9

Ganglionic Blocking Agents; mecamylamine

Question 10

In patients with heart failure taking ganglionic blocking agents, CO ____ due to reduction in peripheral resistance. In normal or HTN patients, CO is ___

Answer 10

increases; reduced