Mitral Valve Flashcards
What is the structure in between the aortic valve and mitral valve?
Intervalvular Fibrosa

Name the papillary muscles of the mitral valve.
1. Anterolateral
2. Posteromedial
Which papillary muscle is likely to rupture and why?
Posteromedial muscle blood supply: Solo blood supply = right coronary artery - posterior interventricular artery (RCA) More likely to rupture (70%) of patients
Anterolateral muscle blood supply: left anterior descending artery - diagonal branch (LAD) and left circumflex artery - obtuse marginal branch (LCX)
What are the other synonymous names for mitral valve Commissures?
Anterior Commissure = Anterior - Lateral Commissure
Posterior Commissure = Posterior - Medial Commissure
What is the normal “Short Axis” measurements of the mitral valve in the Mid Esophageal Long Axis view during end-systole?
ME LAX Normal End Systolic Annulus <36 mm

Why is the mid esophageal long axis the best view for mitral valve high axis measurements?
*Hint: 3 reasons*
- Best place to look for MV Prolapse or excessive leaflet motion (high point of the annulus)
2. Best place to measure vena contracta
- A2 and P2 scallops seen (Most common prolapse to repair easily is P2)
- Measure the end systolic annulus
What is the best view to measure the long axis of the mitral valve?
ME Commissural View
What is the normal “Long Axis” measurement of the mitral valve annulus during end-systole?
<46 mm

What view of the Mitral Valve is seen in the mid esophageal at approximately 0 - 30 degrees?
ME 4 chamber

What view of the Mitral Valve is seen in the mid esophageal at approximately 60 degrees?
ME Commissural View

What scallops are seen in the commissural view of the mitral valve?
P1 = Right
A2 = Center
P3 = Left

What view of the Mitral Valve is seen in the mid esophageal at approximately 90 Degrees?
Mid Esophageal 2 chamber

What view of the Mitral Valve is seen in the mid esophageal at approximately 120 degrees?
Mid Esophageal Long Axis

What view is seen here?

Basal Short Axis View

What view is seen here?

Transgastric 2 chamber view
Mitral Valve Subvalvular Apparatus

What walls of the heart are shown here?

INFERIOR = CLOSE TO THE PROBE
ANTERIOR = AWAY FROM THE PROBE

What papillary muscle is seen here?

Posteromedial Papillary Muscle

What does induction of general anesthesia do to the severity of MR?
Loading conditions change (Afterload and Preload drop)
Severity of MR Underestimated
What is the most common cause of MR in the west?
Myxomatous Degeneration
Myxomatous degeneration is a process that occurs when the valve becomes thickened with formation of small nodules on the edges of the leaflets. This prevents complete closing of the valves and as a result blood can flow backward into the left atrium. The resultant backflow is called mitral regurgitation.
What is the most common cause of MR in developing nations?
Rheumatic Disease
Besides myxomatous degeneration and rheumatic disease, what are some causes of MR?
Ischemia (Pap Muscle Dysfunction and/or rupture)
Cardiomyopathy (Dilated vs. idiopathic hypertrophic subaortic stenosis)
Endocarditis
Congenital (cleft anterior leaflet with AV Canal defect)
Connective Tissue Diseases (SLE, RA, Marfan’s)
Label the Papillary muscles in the TG SAX Mid-Papillary TEE view

Label the Papillary muscles in the Mid Commissural View

What is the Best place to look for MV Prolapse or excessive leaflet motion?
ME LAX (high point of the annulus)
What is the best place to measure vena contracta of mitral valve?
ME LAX
What is the most common prolapse scallop of the mitral valve?
(Most common prolapse to repair easily is P2)
What scallops of the mitral valve are seen in Mid Commissural view of the mitral valve?
P1 (Far Right) - A2 - P3 (Far Left)

What scallops of the mitral valve are seen in 2 chamber view of the mitral valve?
P3 and A1 scallops

What scallops of the mitral valve are seen in Long Axis view of the mitral valve?
P2 and A2

What do you measure in the ME LAX in terms of the mitral valve?
- Anterior leaflet length (Estimates ring for mitral valve repair)
- Vena Contracta
- Assess MVP (High access of the valve)
- End systolic annulus length <36 mm
Draw the posterior and anterior leaftlet scallops of the TG Basal SAX.
Left side = Anterior
RIght side = Posterior
3 on top of image
1 omn bottom of image

What papillary muscle is seen in TG 2 chamber view?
Posteriomedial Papillary muscle always seen

What are the 4 questions you must answer when determining MR TEE evaluation?
- Severity
- Mechanism
- Location of Lesion
- Repairable
What is the most common cause of MR in the west?
Myxomatous Degeneration = non-inflammatory progressive disarray of the valve structure caused by a defect in the mechanical integrity of the leaflet due to the altered synthesis and/or remodeling by type VI collagen
What is the most common cause of MR in developing nations?
Rheumatic
How can ischemia cause mitral insufficiency?
Posteriomedial papillary muscle dysfunction* vs. *rupture
Blood supply: Single from RCA –> PDA (70% of patients)
What are the 3 connective tissue diseases that can cause MR?
SLE
RA
Marfans
What are the 3 different types of leaflet motion?
-
Normal (Type 1)
- Leaftlet is dilated -
Excessive (Type 2)
- Goes away from diseased leaflet -
Restrictive (Type 3)
- Jet goes toward the defective leaflet

What are the three Type 2 types (Excessive) of excessive leaflet motion?
Prolapse
Billowing
Flail

What are the 4 types of MV leaflet motion (Carpentier classification?
type I: normal leaflet motion
type II: excessive leaflet motion
type IIIa: restricted leaflet motionIIIa: leaflet motion restricted in both systole and diastole
IIIb: leaflet motion restricted in diastole

Ajet / Aatria Mitral Regurgitation
What is Mild?
<20 %
Ajet / Aatria Mitral Regurgitation
What is Moderate?
20 - 40%
Ajet / Aatria Mitral Regurgitation
What is Severe?
>40%
Vena Contracta Mitral Regurgitation
What is Mild?
<3 mm
Vena Contracta Mitral Regurgitation
What is Moderate?
3 - 7 mmHg
Vena Contracta Mitral Regurgitation
What is Severe?
> 7 mm
MR Jet Area Mitral Regurgitation
What is Mild?
< 4 cm2
MR Jet Area Mitral Regurgitation
What is Moderate?
4 - 10 cm2
MR Jet Area Mitral Regurgitation
What is Severe?
> 10 cm2
Pulmonary Vein Flow to grade Mitral Regurgitation
What is Mild?
Blunted S

Pulmonary Vein Flow to grade Mitral Regurgitation
What is Moderate?
S < D

Pulmonary Vein Flow to grade Mitral Regurgitation
What is Severe?
S reversal

Mitral Regurgitant Fraction to grade Mitral Regurgitation
What is Mild?
< 30%
Mitral Regurgitant Fraction to grade Mitral Regurgitation
What is Moderate?
30 - 49%
Mitral Regurgitant Fraction to grade Mitral Regurgitation
What is Severe?
>50%
Mitral Regurgitant Volume to grade Mitral Regurgitation
What is Mild?
<30 cm3 (mL)
Mitral Regurgitant Volume to grade Mitral Regurgitation
What is Moderate?
30 - 59 cm3 (mL)
Mitral Regurgitant Volume to grade Mitral Regurgitation
What is Severe?
>60 cm3 (mL)
Mitral Valve Orifice Area (cm2) to grade Mitral Regurgitation
What is Mild?
< 0.2 cm2
Mitral Valve Orifice Area (cm2) to grade Mitral Regurgitation
What is Moderate?
0.2 - 0.39 cm2
Mitral Valve Orifice Area (cm2) to grade Mitral Regurgitation
What is Severe?
>/= 0.4 cm2
PISA radius (mm) to grade Mitral Regurgitation
What is Mild?
< 4 mm
PISA radius (mm) to grade Mitral Regurgitation
What is Moderate?
4 - 10 mm
PISA radius (mm) to grade Mitral Regurgitation
What is Severe?
>10 mm
PISA radius assumes what:
- Alias velocity?
40 cm/sec
PISA radius assumes what:
- VelocityMR Peak ?
VelocityMR Peak = 500 cm/sec
CWD signal strength to grade MR.
What is mild?
Faint
CWD signal strength to grade MR.
What is moderate?
Moderately Dense
CWD signal strength to grade MR.
What is Severe?
Very Dense
What if you have an eccentric MR jet that “hugs” the walls of the LA.
- What is this called?
- What effect is this?
Coanda Effect

When are the two times you can have posterior jet of MR?
- HOCM
- SAM
What are the 6 risk factors for SAM after MV repair
Size of LV?
Small non-dilated LV
What are the 6 risk factors for SAM after MV repair
Annuloplasty size?
Small annuloplasty ring
What are the 6 risk factors for SAM after MV repair
Posterior Leaflet?
XS Post Leaflet Tissue caausing ant displacement of the coapt line

What are the 6 risk factors for SAM after MV repair
C-Sept?
C-Sept <2.5 cm

What are the 6 risk factors for SAM after MV repair
AL/PL Ratio?
AL / PL ratio of <1

What are the 6 risk factors for SAM after MV repair
Anterior Leftlet size
XS Anterior leaflet distal to coaptation point

SAM after MV repair
What C-sept distance is decreased risk?
>3 cm = Decreased risk
<2.5 cm = Increased risk

SAM after MV repair
What AL/PL is decreased risk?
AL / PL >3 = Decreased risk
AL / PL <1 = Increased risk

What is the most common cause of Mitral Stenosis?
Rheumatic Heart Disease
Other than rheumatic disease, what is the cause of mitral stenosis?
LA myxomaaa
Severe mitral annular calcification
Thrombus formation
Parachute MV
Congenital
Subvalvular Mitral Ring
Cortriatiatum Sinister
What is seen here?

As in rheumatic Mitral Stenosis, the anterior mitral leaflet (AMVL) shows diastolic doming or hockey-stick shape. And the posterior mitral leaflet (PMVL) has restricted motion or is totally immobile.
This doming is due to the reduced mobility of the valve tips compared to the base of the leaflets.
How do you calculate the Mitral Valve area using planimetry?
Trace of TG Basal SAX
How do you calculate the Mitral Valve area using pressure half time?
220 / PHT
How do you calculate the Mitral Valve area using deceleration time?
MVA = 759 / DT
How do you calculate the Mitral Valve area using continuity equation?
Mitral Valve Area = [ALVOT x TVILVOT] / TVIMV
How do you calculate the mitral valve area using PISA?
QPISA / VPEAK
What is the mean gradient of mild mitral stenosis?
< 5 mmHg
What is the mean gradient of moderate mitral stenosis?
5 - 10 mmHg
What is the mean gradient of severe mitral stenosis?
>10 mmHg
What is a normal PHT of the mitral valve?
30 - 89
What is a PHT of mild mitral stenosis?
90 - 150
What is a PHT of moderate mitral stenosis?
151 - 219
What is a PHT of severe mitral stenosis?
>220
What is a normal Mitral Valve Area?
>2.5 cm2
What is a Mitral Valve Area with mild Mitral Stenosis?
1.6 - 2.5 cm2
What is a Mitral Valve Area with moderate Mitral Stenosis?
1.0 - 1.5 cm2
What is a Mitral Valve Area with severe Mitral Stenosis?
< 1.0 cm2
What are two problems with using PHT for Mitral Valve area?
1. Decreased LV compliance
2. Severe AI
Rapid rise in LVEDP causing decreased PHT
Overestimates MVA (PHT too low)
Underestimates degree of Mitral Stenosis
What 3 things will give you a higher mean gradient when evaluating Mitral stenosis?
- Severe MR (Increased LAP)
- Higher HR (Increased mean gradient)
- Increased SV (SVMV diastolic inflow)
What 2 things will give you a understimated mean gradients when evaluating Mitral stenosis?
- Angle of Incidence
- LV Active relaxation (Impaired relaxation)
What will give you an overestimated mean gradient when evaluating Mitral stenosis?
Decreased LV Compliance
What does PISA stand for?
Proximal Isovelocity Surface Area (PISA)

What is the PISA equation?
MV area (Hole) = AreaPISA x VelocityALIAS / VelocityPeak
AreaPISA = 2πr2 * [Alpha / 180]
2πr2 = Area of hemisphere
Alpha / 180 = Not a perfect hemisphere
r = Leaflet to the first aliasing velocity
VelocityALIAS = Velocity that aliasing begins to occur
VelocityPeak = Peak through Mitral Valve

What are the steps to obtaining a PISA?
- Color box on the mitral valve
- Adjust the Nyquist Limit to obtain Isovelocity Shells
- Determine your aliasing velocity
4. Measure Radius of isovelocity shell
5. CWD to measure peak velocity of Mitral Valve inflow
- Measure Alpha Angle
What is the equation for Regurgitant Volume of the Mitral Valve?
Regurgitant Volume = SVMV Inflow - SVLVOT
SVMV Inflow = AMV x TVIMV
SVLVOT = [CSALVOT x TVILVOT]
AMV from PHT equation
TVIMV from spectral doppler
SVLVOT from PWD from LVOT measurement

What is the regurgitant fraction?
Backwards Flow / Total Flow
What is the equation for Regurgitant Fraction?
Regurgitant Volume / SVMV Inflow
1. Regurgitant Volume = SVMV Inflow - SVLVOT
SVMV Inflow = AMV x TVIMV
SVLVOT = [CSALVOT x TVILVOT]
AMV from PHT equation
TVIMV from spectral doppler
SVLVOT from PWD from LVOT measurement
2. SVMV Inflow = AMV x TVIMV
What is the equation for the regurgitant oriace area?
ROA = Regurgitant Volume / TVIMR

What is the equation for PISA for MR?
QMRpisa = APISA x VelocityALIAS
What is the equation for EROA MR PISA?
EROA MR PISA = QMRpisa / VMRpeak
What is equation for regurgitant volume?
EROAMRpisa * TVIMR
What mitral valve leaflet is shown?

Anterior Mitral Leaflet
What mitral leaflet is shown?

Anterior Leaflet
What mitral leaflet is shown?

P2 scallop
What method of measuring MVA is not influenced by AI and MR?
PISA
If you measure the vena contracta of a mitral regurgitant jet to determine MR, what view should best evaluate this?
ME Long Axis
Best view to visualze the mitral valve subvalvular apparatus?
TG 2 chamber
What is the most repairable Mitral valve lesion?
P2 prolapse = Most common cause of MR in the west
What MV scallops are seen in the ME Long axis view?
A2 P2

What valve is most commonly affected by rheumatic valvular disease?
Mitral Valve
What view passes through the “high” (Anterior-Posterior) axis of the mtiral valve annulsu and is therefore appropriate view in which to assess leaflet prolapse?
ME Long Axis View
The intensity of the transmitral regurgitant jet relative to the intensity of the transmitral diastolic inflow by CWD reflects what?
MV regurgitant volume

see question on image

A = 0.64 cm2

See attached question

SV = AreaMitral Valve * TVIMV Inflow = 0.64cm2 * 50 cm = 32 mL

See attached question

7 mL


8.2 mm2


B 22%

See table to answer question

Mild MR
R Vol.= 7mL
Rfx = 22%
EOA = 8.2 mm2
Answer the question

Severe MS
(0.6 valve area)
What is Cor triatriatum sinister?
Left atrium is divided into two compartments by a membrane.
The membrane can vary in size and shape and may have one or more openings.
