Mitosis And Meiosis Flashcards

1
Q

Chromosome structure

A

Each replicated chromosome consists of 2 chromatids
Each replicated chromosome contains 2 identical DNA molecules
One chromosome = one DNA molecule before replication

After replication one chromosome -= 2 DNA molecules 2 chromatids

P arm = short
Q arm = long

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2
Q

Metacentric

A

Equal sized p and q arm

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3
Q

Submetacentric

A

P is shorter than q

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4
Q

Acrocentric

A

P arm is almost non existent

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5
Q

Telocentric

A

No p arm

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6
Q

What are homologous chromosome

A

They have the same DNA sequence and have the same genes located on them

Genes on homologous chromosomes maybe be different varients- alleles

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7
Q

Mitosis

A

Cell division for somatic cells

Production of 2 identical daughter ells
-with some chromosome content as parental cell

50 mitosis rounds during early development

Mitotic growth also necessary for some tissue
-epidermis , mucosae,bone marrow and spermatogonia

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8
Q

Prophase

A

Spindles appear

Chromosome condense

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9
Q

Prometaphase

A

Spindle attach to chromosome

Chromosomes condense further

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10
Q

Metaphase

A

Chromosome align

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11
Q

Anaphase

A

Centromeres divide

Sister chromatids move to opposite poles

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12
Q

Telophase

A

Nuclear membrane reforms
Chromosome decondense
Spindle fibres disappear

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13
Q

Cytokinesis

A

Cytoplasm divides

Parent cell becomes 2 daughter cells with identical genetic information.

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14
Q

No disjunction

A

Missegregtion of chromosomes

Leads to aneuploidy- unusual amount of chromosome

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15
Q

Meiosis

A

Special cell division

Chromosome number reduced- one round of replication and 2 rounds of division

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16
Q

Consequences of meiosis

A

Generation of genetic diversity

  • crossing over of genetic material in prophase 1
  • random assortment of chromosomes in metaphase 1

Maintaining constant chromosome number from generation to generation

17
Q

What is the different between meiosis 1 ans 2

A

Homologous pairs of chromosomes lien up ad separate in meiosis 1 and in meiosis 2 chromosomes line up and chromatids separate

18
Q

Spermatogenesis

A

Cell division to produce male gametes

When a spermatogonium undergoes meiosis it becomes a spermatocytes

From spermatocyte (2n) to 4 sperm (n) in approximately 60 days

19
Q

Oogenesis

A

Cell division to produce female gametes

The oocyte arrests into meiosis 1 during prophase 1 and stays thee until puberty and there is the menstrual cycle

Every time we have the menstrual cycle - the oocyte is released from the arrest in prophase 1

From 1 oocyte (2n) to 1 egg (n) plus 3 polar bodes in 12-50 years

20
Q

what is nondisjunction

A

missegregation of chromosomes
leads to aneuploidy
which leads to monosomy- 1 chromatid
trisomy- 3 chromatids