Glucose And Glycolyisis Flashcards

1
Q

How does the Sodium gluose transporter work

A

iTunes the [] gradient for sodium inwards into the cell to provide the energy to drive glucose up its concentration gradient from a low [] gradient t hig in the epithelial cells

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2
Q

What is produced from glycolysis ?

A

NADH
2 ATP net (uses 2)
C6 and c3 intermediates

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3
Q

Features of glycolysis

A
Ecergonic 
Oxidative 
Occurs in all tissues cytosolic 
Can operate anaerobically 
Irreversible 
C6 to 2c3
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4
Q

What enzymes are involved in glycolysis and what do they do

A

Hexokinase- glucokinase in the liver -
- converts gluose to glucose 6P

Phosphofructokinase-1
-key control enzyme
Converts fructose-6-P to fructose 16 bisphosphate

Pyruvate kinase
-converts Phosphoenolpyruvate to pyruvate

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5
Q

Which stages of glycolysis are irreversible?

A

1,3 and 10

Step 3 is the committing step- the rate limiting step

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6
Q

what organs can metabolise lactate into pyruvate

A

the liver and kidney: this allows pyruvate to go through gluconeogenesis to form glucose. Glucose can feed into glycolysis, be fed into circulation, or be used for storage

In the heart|: pyruvate is oxidised directly for energy

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7
Q

What are the three key enzymes in glycolysis?

A

Hexokinase

pyruvate kinase

Phosphofructokinase-1

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8
Q

what is the rate limiting enzyme of glycolysis

A

phosphofructokinase

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