Mitosis Flashcards

1
Q

Define: Cell division

A

Process by which cells make more cells

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2
Q

What are the 2 ways which cell divison can occur?

A

Occur through mitosis (body cells) or meiosis (germ or sex cells)

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3
Q

What is cancer

A

Overactive cell division

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4
Q

Explain the size and DNA location of Eukaryotes

A

Genome large and linear

DNA in nucleus

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5
Q

Explain the size and DNA location of Prokaryotes

A

Genome small and circular
DNA in cytoplasm

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6
Q

Explain G Phase

A

G phase - double the amount of everything needed, cell grows by producing protein

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7
Q

Explain S Phase

A

S phase - dna is duplicated

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8
Q

Explain G2 phase

A

G2 phase - cell prepared to enter into mitosis

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9
Q

Explain M phase

A

M phase (mitosis) - chromosomal separation and cytokinesis

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10
Q

What is interphase

A

Interphase - time between successive mitosis

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11
Q

Explain the phases of the cell cycle

A

Interphase (G, S, G2p phase), Mitosis (PMAT, cytokinesis)

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12
Q

What happens to cells not actively

A
  • May exit cell cycle
  • From G1, enter state of G0
  • These cells are said to be quiescent (inactive)
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13
Q

How many chromosomes of in a human genome

A

23 pairs of chromosomes

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14
Q

How many autosomes and sex cells are in human genomes

A

1-22 is autosomes
23 is sex chromosome - determine sex

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15
Q

What are homologous chromosomes

A
  • Chromosomes that belong together
  • Of common descent
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16
Q

What are centromeres

A

Centromeres - central part of chromosomes important for separating spindle fibres

17
Q

What happens to chromatids in the S phase

A

Through S phase, chromatids double making are sister chromatids (still same amount of chromosomes)

18
Q

What is mitotic cell division

A

Mitotic Cell Division: a single parent cell divides into 2 daughter cells

19
Q

What happens in prophase

A

Chromosomes condense

Centrosomes radiate microtubes and migrate to opposite poles

20
Q

What happens in pro-metaphase

A

Microtubules of the mitotic spindle attach to chromosomes

Nucleus envelope begins to break

21
Q

What happens in metaphase

A

Chromosomes align in center of cell

22
Q

What happens in anaphase

A

Sister chromatids separate and travel to opposite poles

– Sister chromatids become individual chromosomes when the centromere is split

23
Q

What happens in telophase

A

Nuclear envelopes re-form and chromosomes decondense

24
Q

What is cytokinesis

A

Physical process of cell division that divides the cytoplasm of the parent cell into 2 daughter cell

25
How long does it take cells in culture to complete 1 cell cycle
Take 24 hours to complete 1 cell cycle
26
What are ploidy levels
of complete sets of chromosomes in a cell is known as its ploidy
27
What are haploid cells
Cell with 1 complete set of chromosomes in haploid
28
What is the ploidy of haploid cells
1n
29
What are an example of haploid cells
Ex. sperm cell or an egg in vertebrates
30
What are diploid cells
Diploid cell would have 2 complete sets of chromosomes. One from mother, and one from father
31
Whats the ploidy of diploid cells
2n
32
What are examples of diploid cells
Ex. somatic cell such as leaf cell Ex. Skin cell Ex. stem cell in colon
33
What happens to diploid somatic cells after S phase
DNA doubles making a complete set of chromosomes Still a diploid cell
34
Does DNA or ploidy change in mitosis?
Amount of DNA changes but NOT the ploidy levels in Mitosis
35