Miscellaneous Gastroenterology Flashcards
Features of appendicitis
Central pain radiating to RIF
Anorexia
Rovsings sign (press LIF, pain in RIF)
Guarding on abdominal palpation
Rebound tenderness in the RIF (increased pain when suddenly releasing the pressure of deep palpation)
Percussion tenderness (pain and tenderness when percussing the abdomen)
Neutrophil predominant leukocytosis
NB- Rebound tenderness and percussion tenderness suggest peritonitis, potentially indicating a ruptured appendix.
Investigations and management for appendicitis
Clinical diagnosis, but USS useful in young females (pelvic organ pathology)
Laparoscopic appendicectomy with prophylactic IV ABX
How to calculate units of alcohol
Number of millilitres by the %, then divide by 1000
Alcoholic ketoacidosis
Non diabetic euglycaemic form of ketoacidosis (often alcoholics)
Metabolic acidosis with elevated anion gap, ketonaemia, normal or low glucose
Treat (vitamin B1) with infusion of saline and thiamine (always correct thiamine before glucose)
What are carcinoid tumours
Cause carcinoid syndrome- typically liver metastases that release serotonin systematically (also lung)- can also release pituitary hormones eg. ACTH
Features- flushing, diarrhoea, bronchospasm, hypotension, valvular stenosis, pellagra
Investigations and management or carcinoid tumours
Urinary 5-HIAA
Management- somatostatin analogue eg. Octreotide
NB0 cardiac manifestations: pulmonary stenosis and tricuspid insufficiency
Risk factors for bowel ischaemia
Increased age
Emboli- AF, malignancy, infective endocarditis
CVD risk factors
Cocaine
Features of bowel ischaemia
Abdominal pain
Rectal bleeding
Diarrhoea
Fever
Bloods- elevated WCC, lactic acidosis
CT- investigation of choice
Acute mesenteric ischameia
Sudden onset acute abdominal pain
Out of keeping with physical exam findings
Urgent surgery required
Chronic mesenteric ischaemia
Intestinal angina
Colicky, intermittent, abdominal pain
Ischaemic colitis
Acute but transient compromise to blood flow in large bowel- inflammation ulceration and haemorrhage
Most likely to occur in splenic flexture
Thumb printing on x ray
Supportive management
Surgery in severe cases
Metoclopramide
D2 receptor antagonist
Used in management of nausea, GORD, gastroporeis, migraine
Adverse effects of metoclopramide
Extrapyramidal eg, oculogyric crisis, tardive dyskinesia, Parkinsonism
Hyperprolactinameia
Avoid in bowel obstruction, may be helpful in paralytic ileus
Peutz Jeghers syndrome
Hamartomatous polyps in small bowel
Pigmented lesions on lips, oral mucosa, face, palms, soles
Intestinal obstruction (intussusception)
GI bleeding
Adverse effects of PPI’s
Hyponatraemia, hypomagnesia
Osteoporosis- fracture risk
Colitis
Increased risk of c diff infection
Features of refeeding syndrome
Hypophoshphataemia
Hypokalaemia
Hypomagnesia
Abnormal fluid balance
If someone hasn’t eaten for 5 days, feed at no more than 50% of their requirements for 2 days
Small bowel bacterial overgrowth syndrome
Diabetes Mellitus and scleroderma
Similar features to IBS
Hydrogen breath test for diagnosis
Correct underlying disorder and rifaximin (ABX)
Spontaneous bacterial peritonitis
Usually seen in patients with ascites secondary to liver cirrhosis
Can be asymptomatic so have a low threshold for ascitic fluid culture, Fever, Abdominal pain, Deranged bloods (raised WBC, CRP, creatinine or metabolic acidosis), Ileus, Hypotension
Paracentesis- neutrophils >250, usually E. coli when ascitic fluid is cultured
Give prophylaxis to people who have had this before
Vitamin A
Retinol
Deficiency causes nighttime blindness
Vitamin B1
Thiamine
Deficiency- WKS, wet beri beri (heart)
Causes of deficiency- alcohol excess, malnutrition
Dry beri beri
Peripheral neuropathy
Wet beri beri
Dilated cardiomyopathy
Vitamin B3
Niacin
Deficiency causes pellagra- dermatitis, diarrhoea, dementia
Vitamin B6
Pyridoxine
Peripheral neuropathy and sideroblastic anaemia