Case 9- Heart Failure Flashcards

1
Q

Investigations for suspected heart failure

A

ECG (axis deviation/ point to cause)
PFT- exclude respiratory cause
Bloods- FBC, UE, LFT (lack of perfusion) NT-pro-BNP
CXR
TOE

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2
Q

Drugs contraindicated in heart failure

A

NSAIDS
Non dihydropiridines Calcium channel blockers (amlodipine may be used cautiously in controlled heart failure)
Pioglitazone
Moxonidine

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3
Q

Sydenham chorea

A

Involuntary, irregular, nonrepetitive movements of the limbs, neck, head, face sometimes confined to one side (hemichorea)

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4
Q

Erythema marginatum

A

Expanding pink rash with a well defined out er border and central clearing. Trunk and limbs affected, face is spared. Painless and non pruritic

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5
Q

Organisms causing IE

A

Strep viridians/sanguinis (dental hygiene), staph aureus (IVDU), staph epidermidis (if <2 months who had valvular heart surgery), strep bovis (CRC) enterococci, coxiella burnetti (previous ABX use), HÁČEK

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6
Q

Causes of CHF

A

Cardiac- CAD, valvular disease eg. AS, HOCM, uncontrolled AF, HTN

Pulmonary- COPD, pulmonary fibrosis

Drugs- fluoruracil and cisplatin

Autoimmune- amyloidosis, sarcoidosis

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7
Q

Symptoms of CCF (what patient may complain about)

A

Reduced perfusion- fatigue, exercise intolerance

Pulmonary congestion- orthopnoea, PND, white or pink sputum, cardiac wheeze, nocturnal cough

Systemic congestion- peripheral oedema, weight gain

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8
Q

Signs of CCF (what I look for in an exam)

A

Reduced perfusion- cyanosis, tachypnoea, tachycardia

Pulmonary congestion- fine basal crepes (oedema), pleural effusion, S3 heart sound

Systemic congestion- raised JVP, peripheral oedema, hepatomegaly, ascites

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9
Q

Rheumatic fever Sx

A

Constitutional Sx, migratory polyarthritis, pancarditis (endo, myo, pericarditis), valvular lesions, syndeham chorea, erythema marginatum

NB- rheumatic heart disease occurs many years later. In a valve station, ask if they had rheumatic fever as a child

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10
Q

Rheumatic fever investigations

A

Throat cultures
Jones criteria calculation
Bloods- ESR, CRP, WBC, blood cultures, rapid antigen test for group A streptococci
ECG
CXR
TOE

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11
Q

Sx of IE

A

Constitutional Sx eg. tachycardia, general malaise, weakness, night sweats, weight loss. Dyspnoea, cough, pleuritic chest pain, arthralgia, myalgia, finger clubbing, cardiac murmur, peripheral stigmata (Roth, Osler (immunologic- also SLE, gonorrhoea, typhoid and haemolysis) Jane way (vascular), splinter haemorrhages (conjunctiva or fingernails), abdominal pain or stroke (emboli))

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12
Q

AF aetiology

A

CAD, HTN, hyperthyroidism, alcohol abuse, infections/sepsis

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13
Q

Investigations for palpitations, possible AF

A

Bloods- troponin?, NT proBNP, FBC (anaemia, infection), TSH (thyrotoxicosis), UE (electrolyte disturbance), toxicology (cocaine)

ECG- irregularly irregular RR intervals, P waves indiscernible, tachycardia, narrow QRS complex

TOE- rule out underlying structural disease

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14
Q

IE Investigations

A

ECG
Bloods- 3 separate cultures (preferably different sites), WCC, ESR, CRP
CXR (emboli may travel to lungs and cause cavities)
TOE or TTE (latter is quicker and less invasive)
CT- look for emboli

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15
Q

Valvular disease investigations

A

ECG- any hypertrophy?
Bloods- TFT, FBC (anaemia), NT-pro-BNP
CXR- calcification of aortic valve
Echo- TOE

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16
Q

CHA2DS2VASC

A

Whether someone with AF needs anticoagulation or not

CHF
HTN
Age (65-74:1, 75+:2)
DM
(Previous) Stroke/TIA/thromboembolism (2)
Vascular disease
Sex (female:1)

0- no
1 (female)- no
1 (male)- consider
2- yes

NB- anyone with a history of AF, not just current persistent AF (ie. Those with asymptomatic PAF or first onset)

NB- ensure a transthoracic echocardiogram has been done to exclude valvular heart disease (esp. people who score 0), which in combination with AF is an absolute indication for anticoagulation.

NB- certain people with AF will score 0: they wont need anticoagulation (although they may still have rate control eg. beta blocker if tachycardia is present, and they will definitely need an echocardiogram to exclude structural heart disease (which add AF requires anticoagulation)

NB- If valvular heart disease is present alongside AF, this indicates anticoagulation as it increases the risk of stroke.

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17
Q

HASBLED

A

OLD/ REDUNDANT scoring system for establishing patients risk of major bleeding whilst on anticoagulation

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18
Q

Pill in the pocket approach

A

Flecanide for paroxysmal AF (avoid in atrial flutter)

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19
Q

Treatment for bradycardia/AV nodal block

A

Stable- observe

Unstable- atropine (6 doses), then noradrenaline, then a defibrillator/ pacing etc.

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20
Q

Aortic stenosis

A

SAD- syncope, angina, dyspnoea

NB- nitrates contraindicated

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21
Q

Aortic regurgitation (chronic)

A

Palpitations, symptoms of LHS heart failure (lung symptoms), exertional dyspnoea, angina, fatigability, syncope

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22
Q

Mitral stenosis

A

Dyspnoea (PND), orthopnoea, haemoptysis, AF, then RHF Sx (generally LHS first)

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23
Q

Mitral regurgitation (chronic)

A

Dyspnoea, palpitations, LHS heart failure Sx (lung symptoms)

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24
Q

Valvular pathologies

A

4 under most pressure in LHS often cause LHS Sx of heart failure first (lungs)

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25
Heart failure management
NB- loop diuretics (furosemide) initially for Sx control 1st line ACE-I (or ARB), beta blocker (together if reduced LVEF) 2nd line aldosterone receptor antagonist 3rd line ivabradine, hydralazine etc., but if widened QRS complex (LBBB), try cardiac resynchronisation Annual flu vaccine, one off pneumococcal Cardiac rehab Supportive eg. Exercise, diet, sleep etc. NB- patients should have their U&Es monitored closely whilst on diuretics, ACE inhibitors and aldosterone antagonists as all three medications can cause electrolyte disturbances.
26
Heart failure CXR findings
ABCDE Alveolar shadowing (batwing appearance) B lines (interstitial oedema) Cardiomegaly Dilated upper lobe veins Effusion (blunted costiohrenic angles)
27
Cardio version
3 week anticoagulation and echocardiogram has excluded presence of thrombus
28
What is VT
A broad complex tachycardia that has the potential to precipitate VF
29
Polymorphic VT
Eg. Torsades de pointes. Precipitated by prolonged QTc (which can be triggered by macrolide eg, clarithromycin)
30
Monomorphic VT
Usually. Caused by an MI
31
Causes of a prolonged QTc
Congenital- Jervell-Lange-Nielsen syndrome (deafness, potassium channels), Romano-Ward (no deafness) Drugs- amiodarone, TCA, antipsychotics, chloroquine, terfenadine (antihistamine), sotalol, SSRI (citalopram), erythromycin (&clarith) Other- hypocalcaemia, hypokalaemia, hypomagnesia, acute MI, myocarditis, hypothermia, SAH
32
Management of VT
Adverse signs- shock, systolic BP <90, myocardial ischaemia, syncope, heart failure, 3 synchronised DC shocks No adverse signs- amiodarone, lidocaine NB- drug therapy fails, use an ICD NB- don’t use verapamil in VT
33
Acute management of SVT
If adverse signs- 3 synchronised DC shocks Vagal manoeuvres eg. Valsalva, carotid sinus massage IV adenosine- 6mg, 12mg, 12mg (not in asthmatics- use verapamil) Electrical cardio version
34
Prevention of SVT episodes
Beta blockers Radio frequency ablation
35
Management of a prolonged QTc
Avoid drugs that precipitate it and strenuous exercise Beta blockers (not sotalol) ICD high risk cases
36
Management of Torsades de pointes
IV magnesium sulphate
37
Management of peri arrest bradycardia
Adverse signs present indicate treatment- shock, systolic BP <90, myocardial ischaemia, syncope, heart failure Atropine (500mcg IV, up to 3mg) Transcutaneous pacing Adrenaline infusion Trans venous pacing
38
Risks for asystole
Complete heart block with broad QRS Recent systole Mobitz type II AV block Ventricular pause > 3 seconds
39
Reversible causes of cardiac arrest
H’s- hypoxia, hypovolameia, electrolyte imbalances (eg. Hyper/hypokalaemia, hypoglycaemia, hypocalcaemia, other metabolic disorders), hypothermia T’s- thrombosis (coronary or pulmonary), tension pneumothorax, tamponade (cardiac), toxins
40
Adult advanced life support management
See picture in gallery
41
Administering adenosine
Large proximal cannula (grey)
42
Contraindications to adenosine
Asthma COPD Heart failure Heart block Severe hypotension NB- use verapamil instead
43
Medications contraindicated in people with WPW and AF
Antiarrhythmics eg. Beta blocker, calcium channel blocker, adenosine etc.
44
What is bigeminy
Ventricular ectopics that happen after every sinus beat
45
Management of bigeminy
Bloods- anaemia, electrolyte disturbance, thyroid abnormalities No treatment in healthy individuals
46
Treatment for stable bradycardias
Observe
47
What is acute LVF
Left ventricle is unable to adequately move blood through the left side of the heart causing a back log into the pulmonary circulation
48
Causes of acute LVF
Iatrogenic (aggressive IV fluids in a frail old person) Sepsis MI Arrhythmias
49
Typical presentation of acute LVF
Rapid onset breathlessness with type 1 respiratory failure (no increase in CO2)
50
Signs and symptoms of acute LVF
Typical signs and symptoms of heart failure
51
Investigations for acute LVF
OBS and clinical exam (hydration status) ECG Bloods- ABG, BNP, FBC, UE, troponin if suspect MI CXR
52
Causes of a raised BNP
LVF/HF Tachycardia Sepsis PE Renal impairment COPD
53
Management of acute LVF
Pour SOD Pour away (stop) the IV fluids Sit up the patient Oxygen Diuretics (IV frusemide 40mg stat) NB- monitor fluid balance and stop beta blockers when pulse below 50, 2/3 heart block, or shock NB- Acute heart failure not responding to treatment - consider CPAP
54
Options to consider in severe acute pulmonary oedema or cardiogenic shock
NIV CPAP Inotropes (noradrenaline) HDU ITU
55
How many blood cultures to take in suspected IE
3
56
First detected episode of AF
First time someone is found to have AF
57
Paroxysmal AF
When a patient has 2 or more episodes of AF. If episodes of AF terminate spontaneously
58
Persistent AF
If the arrhythmia is not self-terminating ie. requires flecanide
59
Permanent AF
There is continuous atrial fibrillation which cannot be cardioverted or if attempts to do so are deemed inappropriate
60
Rate control vs rhythm control
NICE advocate using a rate control strategy except in a number of specific situations such as coexistent heart failure, first onset AF or where there is an obvious reversible cause.
61
Criteria for rate control management
A beta-blocker or a rate-limiting calcium channel blocker (e.g. diltiazem) is used first-line If rate control isn't achieved, any 2 of a beta blocker, diltiazem, and digoxin can be combined
62
Criteria for rhythm control management
Short duration of symptoms (less than 48 hours) or be anticoagulated for 3 weeks prior to attempting electrical cardioversion.
63
Catheter ablation for AF
Those with AF who have not responded to or wish to avoid, antiarrhythmic medication. Anticoagulation should be used 4 weeks before and during the procedure, and if CHADVASC=0, continue for 2 months, or if =1, continue indefinitely
64
Rhythm control in AF- cardioversion within 48 hours
Cardioverted using either: electrical - 'DC cardioversion' pharmacology - amiodarone if structural heart disease, flecainide or amiodarone in those without structural heart disease Give heparin first either way Following electrical cardioversion patients should be anticoagulated for at least 4 weeks.
65
Cardioversion after 48 hours
Anticoagulation should be given for at least 3 weeks prior to cardioversion. An alternative strategy is to perform a transoesophageal echo (TOE) to exclude a left atrial appendage (LAA) thrombus- give heparin and cardiovert immediately Following electrical cardioversion patients should be anticoagulated for at least 4 weeks.
66
ORBIT scoring system
Used to deduce risk of bleed on anticoagulant- falls are not a reason to withhold anticoagulation Haemoglobin <130 g/L for males and < 120 g/L for females, (2 points) Age > 74 years (1 point) Bleeding history (GI bleeding, intracranial bleeding or haemorrhagic stroke) (2 points) Renal impairment (GFR < 60 mL/min/1.73m2) (1 point) Treatment with antiplatelet agents (1 point)
67
Anticoagulants in AF
DOACs first line Warfarin second line NB- not aspirin NB- In general, DOACs are used as first-line agents in atrial fibrillation. However, there are some important exceptions e.g. if the patient has moderate or severe mitral stenosis, or if the DOAC was not tolerated (use warfarin)
68
Ivabradine
sinus rhythm > 75/min and a left ventricular fraction < 35%
69
sacubitril-valsartan
criteria: left ventricular fraction < 35% is considered in heart failure with reduced ejection fraction who are symptomatic on ACE inhibitors or ARBs should be initiated following ACEi or ARB wash-out period
70
Digoxin
it is strongly indicated if there is coexistent atrial fibrillation (and sedentary)
71
Cardiac resynchronisation therapy
indications include a widened QRS (e.g. left bundle branch block) complex on ECG
72
Hydralazine + nitrate
this may be particularly indicated in Afro-Caribbean patients
73
Aortic stenosis surgical management criteria
Either a) Symptomatic b) Asymptomatic but valvular gradient is greater than 40 and features such as LV systolic dysfunction
74
What can give a falsely low Nt-proBNP
ACE-i
75
When is DC cardioversion recommended for AF
when there is life-threatening haemodynamic instability caused by new-onset atrial fibrillation (non-life threatening, then rate/rhythm, control)
76
Management of IE
Amoxicillin (or vancomycin if penicillin allergic/prosthetic valve) Indications for surgery; severe valvular incompetence aortic abscess (often indicated by a lengthening PR interval) infections resistant to antibiotics/fungal infections cardiac failure refractory to standard medical treatment recurrent emboli after antibiotic therapy
77
Murmurs- inspiration and expiration
Generally speaking, murmurs heard best in expiration suggest a left valve problem (Expiration, lEft), and murmurs heard best in inspiration suggest a right valve problem (Inspiration, rIght).
78
Cardiorenal syndrome
This occurs when the cardiac output drops sufficiently to result in renal dysfunction. Whilst it is often thought that in renal dysfunction, nephrotoxic agents need to be withheld and doses of diuretics tapered. In this case, it is the hypervolaemic state that has contributed to reduced cardiac output (shifting the Frank-Starling curve). This means that increased doses of diuretics are required to improve cardiac contractility, improve cardiac output, and thus increase renal perfusion. It would be sensible to start an infusion of furosemide at a reasonably high dose.
79
Mitral stenosis management
Asymptomatic- regular follow up, no surgery Symptomatic -Balloon valvuloplasty for less severe disease -Mitral commissurotomy or replacement for severe disease