Miscellaneous Flashcards
what is the true negative test?
specificity
what is the true positive test?
sensitivity
What is specificity
Measure percent of the patients without the disease that are identified correctly.
What is sensitivity
Measure percentage of people with the disease that are identified.
What is the formula for specificity (true neg test)
Divide true negs by total number of patients without the disease.
what is the formula for sensitivity (true positives)?
Divide number of positives by total number of people with the disease.
Tell apart specificity and sensitivity
specificity identifies those that don’t have the disease and sensitivity identifies those that do have the disease.
What is the difference between a phase II and phase III trial.
Phase II looks at safety and effectiveness.
Phase III compares to standard therapy
What is sensitivity and it’s formula
ability to identify the number of positive people with the disease. true positives rate = true positives + false negatives
What is specificity
ability to identify those that don’t have the disease.
what is sensitivity also called? and
true positive rate
What is specificity also called
true negative rate
How do you calculate the Positive predictive value
true positives / true positives +false positives
What does prevalence mean
Number of cases in a given population at a given point in time.
What does incidence mean.
number of new cases reported over a given time.
how to tell the ester from the amide anesthetics from their chemical structure
The aromatic ring is connected to a carbon in the ester form and a N in the amide form.
what part of the chemical formula of anesthetics is responsible for the potentcy?
The aromatic ring as it is lipophilic
The more lipophilic the more enters the cell.
What detrimines the onset of action and the duration of an anesthetic?
The amine group
What is genetic polymorphism
when multiple alleles can occupy a gene locus in the same population variations my arise as mutations
what is genetic imprinting
when gene expression depends on whether it was inheritited from the mother or father.
In stageing for MF what do each of the letters represent.
T
N
M
B
T skin (1<10%, 2,>10% 3Nodules 4 Erythema)
Nodes
M visceral involvement (o no, 1 yes)
B sezary cells (0 5%
