Miscellaneous Flashcards

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1
Q

what is the true negative test?

A

specificity

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2
Q

what is the true positive test?

A

sensitivity

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3
Q

What is specificity

A

Measure percent of the patients without the disease that are identified correctly.

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4
Q

What is sensitivity

A

Measure percentage of people with the disease that are identified.

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5
Q

What is the formula for specificity (true neg test)

A

Divide true negs by total number of patients without the disease.

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6
Q

what is the formula for sensitivity (true positives)?

A

Divide number of positives by total number of people with the disease.

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7
Q

Tell apart specificity and sensitivity

A

specificity identifies those that don’t have the disease and sensitivity identifies those that do have the disease.

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8
Q

What is the difference between a phase II and phase III trial.

A

Phase II looks at safety and effectiveness.
Phase III compares to standard therapy

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9
Q

What is sensitivity and it’s formula

A

ability to identify the number of positive people with the disease. true positives rate = true positives + false negatives

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10
Q

What is specificity

A

ability to identify those that don’t have the disease.

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11
Q

what is sensitivity also called? and

A

true positive rate

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12
Q

What is specificity also called

A

true negative rate

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13
Q

How do you calculate the Positive predictive value

A

true positives / true positives +false positives

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14
Q

What does prevalence mean

A

Number of cases in a given population at a given point in time.

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15
Q

What does incidence mean.

A

number of new cases reported over a given time.

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16
Q

how to tell the ester from the amide anesthetics from their chemical structure

A

The aromatic ring is connected to a carbon in the ester form and a N in the amide form.

17
Q

what part of the chemical formula of anesthetics is responsible for the potentcy?

A

The aromatic ring as it is lipophilic

The more lipophilic the more enters the cell.

18
Q

What detrimines the onset of action and the duration of an anesthetic?

A

The amine group

19
Q

What is genetic polymorphism

A

when multiple alleles can occupy a gene locus in the same population variations my arise as mutations

20
Q

what is genetic imprinting

A

when gene expression depends on whether it was inheritited from the mother or father.

21
Q
A
22
Q

In stageing for MF what do each of the letters represent.

T

N

M

B

A

T skin (1<10%, 2,>10% 3Nodules 4 Erythema)

Nodes

M visceral involvement (o no, 1 yes)

B sezary cells (0 5%