Misc 4 Flashcards

1
Q

Describe euthyroid sick syndrome

A

Abnormal TFTs in euthyroid pts with nonthyroidal systemic illness

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2
Q

What is ectopia lentis?

A

Lens dislocation = common in Marfans

Sudden deterioration of vision, usually following trauma

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3
Q

Medical management of serotonin syndrome

A

Cyproheptadine (5-HT2A antagonist)

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4
Q

What is unique to the DSM criteria for bulimia?

A

Loss of control when eating

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5
Q

Describe aortic arch dissection

A

Usually due to trauma

Widened mediastinum - needs CT

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6
Q

What is telogen effluvium?

A

Shedding hair loss that occurs after a stressful event (3 mths after)

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7
Q

What is anagen effluvium?

A

Diffuse hair loss from chemo

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8
Q

What is the cut off for portal HTN?

A

pressure gradient >5

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9
Q

What features are common in portal HTN?

A

Caput medusae
Hemorrhoids
Splenomegaly
Esophageal varices

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10
Q

What is the medical management of essential tremor?

A

Younger pts = propranolol

Older = primidone

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11
Q

Management of OCD

A

SSRIs or clomipramine

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12
Q

Describe superior mesenteric artery syndrome

A

Rapid weight loss + GI symptoms (epigastric pain, N/V, early satiety)
Compression of duodenum by aorta + SMA
Diagnose with CT
AXR shows gastric distention

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13
Q

What genetic conditions cause an increase + decrease in FSH?

A
Increase = Turners 
Decrease = Kallmans
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14
Q

What investigation would you do for mulerian agenesis?

A

MRI urography

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15
Q

Describe mulerian agenesis

A

Mayer–Rokitansky–Küster–Hauser syndrome
Absent uterus
Primary amenorrhea with normal secondary sexual characteristics eg breast tissue
46 XX

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16
Q

What is the triad of symptoms in Lofgrens?

A

Bilateral hilar lymphadenopathy
Erythema nodosum
Arthralgia

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17
Q

What meds are used to stimulate the heart in hypothermia?

A

Bretylium

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18
Q

What rate of warming is appropriate in hypothermia or frost bite?

A

> 2C an hour

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19
Q

What are the CXR findings in transient tachypnea of newborn?

A

Similar to HF but no enlarged heart

Prominent vasculature

20
Q

What is pontiac fever?

A

Acute febrile illness caused by legionella, no resp symptoms

21
Q

What is the Widal test?

A

Measures ab against typhoid antigens

22
Q

Management of epididymitis

A

Ceftrixone IM + doxycycline 7 days

23
Q

What is neurocardiogenic syncope?

A

Vasovagal + vasodepressor
Commonest form
In absence of other forms, this is the most likely

24
Q

What is situational syncope?

A

Syncope during cough, dysphagia, constipation, micturition

25
Q

What is carotid sinus hypersensitivity syncope?

A

Syncope while shaving, wearing tight collars or turning head to side

26
Q

What is the management of central retinal artery occlusion?

A

Ocular massage + carbogen therapy

27
Q

What is the management of diabetic eye disease?

A

Laser photocoagulation + ranibizumab

28
Q

What is the threshold of reduced Hb required for cyanosis?

A

<50

29
Q

When does the O2-Hb curve flatten (aka when pulse oximetry is insensitive to change)

A

Above 60

30
Q

What is the most common cause of fetal growth restriction?

A

Maternal HTN

31
Q

What is the most common cause of pancreatitis?

A

Biliary tract disease

32
Q

What is the main complication post kidney transplant + what is diagnostic of this?

A

Viral infections = ‘buffy coat’ inclusion bodies

CMV pneumonitis

33
Q

Describe S+S of TTP + management

A
Pentad of:
Hemolytic anemia 
Thrombocytopenic purpura 
Neuro abnormalities 
Fever
Renal disease 

Managed with plasma exchange, steroids, rituximab

34
Q

What is nail fold microscopy useful in assessing?

A

Cause of raynauds - in secondary causes, nail fold capillaries are distorted + dilated

35
Q

Describe the 3 stages of eosinophilic granulomatous polyangitis

A

1) allergy - asthma/ allergic rhinitis - inflammation of nasal passage can lead to polyps
2) eosinophilia
3) vasculitis of small + medium vessels leading to kidney, lung, GI tract + heart damage

36
Q

What are the cardinal S+S of nephritic syndrome?

A

Proteinuria
Haematuria
HTN
Oliguria

37
Q

Describe symptoms of lateral medullary syndrome

A
Ipsilateral ataxia 
Nystagmus 
Dysphagia 
Facial numbness 
Cranial nerve palsy 
Contralateral hemisensory loss
38
Q

Presentation of primary hyperaldosteronism

A

HTN
Hypernatraemia
Hypokalaemia

Due to increase in aldosterone leading to increased Na resorption + excretion of K = causing HTN

39
Q

Signs of right sided heart failure

A

Raised JVP
Ankle oedema
Hepatomegaly

40
Q

What info is needed to calculate modified Glasgow score for pancreatitis?

A
PANCREAS
PaO2 <8
Age >55
Neutrophilia >15 
Calcium <2 
Renal function (urea >16)
Enzymes LDH + AST 
Albumin <32 
Sugar (glucose) >10
41
Q

What is nicorandil an example of, what is it mainly used for and what are the key SE?

A

K channel activator
Good for angina
SE: headache, flushing, anal ulceration

42
Q

Describe presentation of 3rd nerve palsy

A

Large fixed pupul
Ptosis
Inability to adduct or supraduct eye

43
Q

What visual field defect is common with a pituitary lesion?

A

Bi temporal hemianopia due to compression of optic chiasm

44
Q

What is Hoover’s sign?

A

Distinguishes between organic + functional cause of lower leg weakness
If the pt is making an effort, the normal limb pushes down when pt tries to lift ‘weak’ leg

45
Q

What is Hoffman’s sign?

A

Reflex test to investigate corticospinal tract lesions

46
Q

What is an anti-Jo ab indicative of?

A

(Dermato)myositis