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D&T 3 test 2 > Miller > Flashcards

Miller Flashcards

1
Q

failure to complete separation from esophagus results in

A

TE fistula

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2
Q

what day does pulmonary arteries arise

A

44

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3
Q

what day are R and L bronchi present

A

28

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4
Q

when does pseudoglandular stage occur

A

5th to 17th week gestation

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5
Q

what is pseudoglandular stage

A

period of rapid branching of the pulmonary tree

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6
Q

when does canalicular stage occur

A

16-24 weeks

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7
Q

what is canalicular stage

A
  • capillary bed expands and endothelium thins

- surfactant begin production

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8
Q

what accelerates tissue thinning and surfactant production

A

glucocorticoids

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9
Q

what is alveolar capillary dysplasia

A

capillary beds fail to form properly

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10
Q

when does saccular stage occur

A

28- 38

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11
Q

what happens in saccular stage

A
  • decrease mesenchymal tissue

- increase type II cell

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12
Q

how does maternal diabetes impact baby

A

decreases surfactant production

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13
Q

when does alveolar stage occur

A

36- 2/3 yrs

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14
Q

what does pulmonary vascular change in alveolar stage

A

decrease smooth muscle

decrease pulmonary vascular resistance

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15
Q

what does VEGF do?

A

promotes angiogenesis

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16
Q

what does retinoic acid do

A
  • increase alveolarization

- may decrease broncho pulmonary dysplasia

17
Q

how does estrogen and testosterone change

A

estrogen: adequate levels of surfactant production
testosterone: slows lung development

18
Q

surfactant protein A recycled by

A

type II pneumocyte

19
Q

what is opsonin

A

phagocytosis and kills certain bacteria and fungi

20
Q

can a baby still live with deficient surfactant protein A

A

yes

21
Q

what is surfactant protein B required for

A

extra-uterine life

22
Q

can a baby still live with deficient surfactant protein B

A

no

23
Q

what activates surfactant protein C

A

SP-B

24
Q

function of surfactant protein C

A

recruit phospholipids to lipid layers

25
Q

can a baby still live with deficient surfactant protein C

A

yes

26
Q

function of surfactant protein D

A

innate immunity

27
Q

what increases surfactant secretion

A

glucocorticoids
estrogen
thyroid hormone

28
Q

what decreases surfactant secretion

A

high levels of circulating insulin

29
Q

how does Betamethasone impact lung development

A

increase surfactant production
decrease alveolar division
decrease alveolar length

30
Q

what happens when Betamethasone is give to fetus

A

improves lung maturation

31
Q

what happens when Betamethasone is give to mother

A

decrease fetal body

32
Q

starburst fluid in lymphatic tissue

A

transient tachypnea of newborn

retained fetal lung fluid

D&T 3 test 2 (14 decks)

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