Midterm- Lecture 2 (Ch 2) Flashcards

1
Q

What is primary aging?

A

Physical changes that are gradual, shared and largely inevitable as people grow older

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2
Q

What is secondary aging?

A

Physical changes that are sudden, not shared and often caused by disease, poor health habits, and environmental events as people grow older

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3
Q

What are free radicals?

A

Molecules or atoms that possess an unpaired electron

By products of cell metabolism

Garbage of normal metabolism builds up and causes aging

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4
Q

What are antioxidants?

A

Vitamins and vitamin like substances used to fight and protect against oxidative damage from free radicals

No good science to it

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5
Q

What is replicating senescence?

A

The state in which older cells stop diving

Age because of the limited amount of good cells

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6
Q

What is the Hayflick limit?

A

There are only a number of cell divisions that can happen before reaching replicative senescence

How much cell division we have is as long as we’re gonna live

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7
Q

What is the telomere length?

A

Lengths of repeating DNA that chromosomes have on their tips

Telomere gets shorter every time elk replicates

Shorter it gets the less good replication you have and can trigger a disease

Disease processes more in adults than young people

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8
Q

What is caloric restriction?

A

Diet in which calories are severely reduced but contain essential nutrients

Not a promising theory

Stable primary intake and increase health and longevity

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9
Q

What is reservatrol?

A

A substance doing in red wine that extended the life span of yeast, worms, flies and mice

Did not work on humans

Use to offset caloric restriction

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10
Q

What is rapamycin?

A

Inhibits cell growth

More promising

Side effects

Increase risk of diabetes

Weakens ability to stabilize sugar in your body

Drug found in easter island

Use to offset caloric restriction

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11
Q

What is weight and body composition?

A

Changes in total body weight and where weight is distributed

Fat accumulates in abdomen and leaves face in middle age

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12
Q

What is obesity and BMI?

A

Condition in which ones weight to height ratio increases to a point that has an adverse effect on health

Measured by body mass index

Less than 19- underweight
19 to 24- normal
25 to 29- overweight
30 and higher- obese

Later stage older adults lose weight because of decreased muscle mass and bone density (72-74)

More than 1/3 obese

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13
Q

Do the senses decline with age?

A

Yes

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14
Q

What are the risk factors affecting the senses?

A

Genetics, ethnicity, personal lifestyle behaviors, other diseases

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15
Q

What is osteoporosis?

A

Bone density loss due to calcium loss or OA

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16
Q

How is loss of vision defined?

A

A serious visual loss that is incorrect able by medical or surgical intervention or with eyeglasses

17
Q

What is the percentage of older people affected by vision loss?

What is the percentage of people of age 85 have age related vision problems?

A

18% of older pop

30% of people age of 85

18
Q

What is support structure changes?

A

Loss of subcutaneous fat and decreased tone and elasticity

Facial structure changes and eyes start to look sunken

Loss of elasticity in the face

Skin redundancy- eyelids dripping over

19
Q

What does decreased tear production lead to?

A

Dry eyes

20
Q

What is decreased convergence?

A

Poor eye coordination and difficulty focusing both eyes at the same time on something that is close to you

Need glasses

21
Q

What happens to your cornea as you age?

A

Flattens, becomes thicker, more rigid after 60-65

Blurred vision

22
Q

What happens to your sclera, pupil and iris as you age?

A

Degenerative changes resulting in gradual loss of visual activity (seeing things sharply)

Difficulty seeing in low light conditions

23
Q

What happens to your lens as you age?

A

Increased density and rigidity

Affects near and far vision

Loss of color sensitivity which affects visual acuity

Decreased accommodation- (ability for lens to change shape)- can’t refocus from things far and near

24
Q

What are age related nervous system changes?

A

Slower processing of visual stimuli and therefore need to see stimuli longer for accurate identification

25
Q

What is presbyopia?

A

Near vision loss

Reduced visual acuity or loss of near vision

Age related (40-50)

Lens of eye becomes less flexible

Adjust focus between things that are far and close to you is difficult

26
Q

What is cataracts?

A

Protein degeneration and aggregation on the lens resulting in opacity (lens becomes cloudy and milky)

Decreased visual acuity, blurred vision, altered color perception, sensitivity to flare and image distortion

Correctable by surgical procedure

Most common

Adults over 80

Lens is yellow everything is cued

27
Q

What is age- related macular degeneration?

A

A loss of central vision

Affects people after the age of 50

30% of pop b/n 75-81

Primary cause of visual impairment

More common among Caucasian, smoking, genetics

28
Q

What is glaucoma?

A

Loss of peripheral vision

A group of diseases characterized by progressive optic nerve damage

Can be treated medically or surgically depending on stage

Get tunnel vision

29
Q

What is diabetic retinopathy?

A

Resulting from damage to the blood vessel if the retina

If blood vessels rupture can lead to blindness and can happen from retinal edema

Rupturing blood vessels in retina can cause scotomas

30
Q

What are scotomas?

A

Visual field deficits

Can leave black pathed in the visual field

Can move around- floaters in the eye