Midterm- Lecture 2 (Ch 2) Flashcards
What is primary aging?
Physical changes that are gradual, shared and largely inevitable as people grow older
What is secondary aging?
Physical changes that are sudden, not shared and often caused by disease, poor health habits, and environmental events as people grow older
What are free radicals?
Molecules or atoms that possess an unpaired electron
By products of cell metabolism
Garbage of normal metabolism builds up and causes aging
What are antioxidants?
Vitamins and vitamin like substances used to fight and protect against oxidative damage from free radicals
No good science to it
What is replicating senescence?
The state in which older cells stop diving
Age because of the limited amount of good cells
What is the Hayflick limit?
There are only a number of cell divisions that can happen before reaching replicative senescence
How much cell division we have is as long as we’re gonna live
What is the telomere length?
Lengths of repeating DNA that chromosomes have on their tips
Telomere gets shorter every time elk replicates
Shorter it gets the less good replication you have and can trigger a disease
Disease processes more in adults than young people
What is caloric restriction?
Diet in which calories are severely reduced but contain essential nutrients
Not a promising theory
Stable primary intake and increase health and longevity
What is reservatrol?
A substance doing in red wine that extended the life span of yeast, worms, flies and mice
Did not work on humans
Use to offset caloric restriction
What is rapamycin?
Inhibits cell growth
More promising
Side effects
Increase risk of diabetes
Weakens ability to stabilize sugar in your body
Drug found in easter island
Use to offset caloric restriction
What is weight and body composition?
Changes in total body weight and where weight is distributed
Fat accumulates in abdomen and leaves face in middle age
What is obesity and BMI?
Condition in which ones weight to height ratio increases to a point that has an adverse effect on health
Measured by body mass index
Less than 19- underweight
19 to 24- normal
25 to 29- overweight
30 and higher- obese
Later stage older adults lose weight because of decreased muscle mass and bone density (72-74)
More than 1/3 obese
Do the senses decline with age?
Yes
What are the risk factors affecting the senses?
Genetics, ethnicity, personal lifestyle behaviors, other diseases
What is osteoporosis?
Bone density loss due to calcium loss or OA