MIDAZOLAM (VERSED) Flashcards
CLASS
SHORT-ACTING BENZODIAZEPINE
DESCRIPTION
WATER SOLUBLE BENZO. THAT MAY BE ADMINISTERED FOR CONSCIOUS SEDATION TO RELIEVE APPREHENSION OR IMPAIR MEMORY
ONSET & DURATION
ONSET: IV: 1-3 MINUTES; DOSE DEPENDENT
DURATION: 2-6 HOURS; DOSE DEPENDENT
INDICATIONS
-PREMEDICATIONS FOR TRACHEAL INTUBATION, CARDIOVERSION OR OTHER PAINFUL PROCEDURES
-SEIZURES IN CHILDREN WHEN OTHER BENZODIAZEPINES ARE NOT EFFECTIVE
CONTRADICTIONS
HYPERSENSITIVITY, GLAUCOMA, SHOCK, ALCOHOL INTOXICATION, DEPRESSED VITAL SIGNS,
ADVERSE REACTIONS
RESPIRATORY DEPRESSION, HICCUPS, COUGH, OVERSEDATION, PAIN AT THE EJECTION SITE, NAUSEA AND VOMITING, HEADACHE, BLURRED VISION, HYPOTENSION, RESPIRATORY ARREST
MIDAZOLAM INTERACTIONS
MIDAZOLAM SHOULD NOT BE GIVEN TO PT WHO HAVE TAKEN CNS DEPRESSANTS UNLESS FOR PROCEDURAL SEDATION OR SIMILAR PURPOSE IN A CONTROLLED SETTING.
HOW MIDAZOLAM IS SUPPLIED
2-, 5-,10- ML VIALS (1MG/ML)
1-, 2-, 5-, 10 ML VIALS (5MG/ ML)
DOSAGE AND ADMINISTRAION
0.1 MG/KG IV UP TO 10 MG. CONSIDER STARTING AT 1-2.5 MG BY SLOW IV PUSH IN ADULTS.
EXCITED DELIRIUM- 5MG IV/IM/IN
END-OF-LIFE CARE- 2-5 MG IV
SPECIAL CONSIDERATIONS
PREGNANCY SAFTEY- CATEGORY D
MIDAZOLAM HAS BEEN ASSOCIATED WITH RESPIRATORY ARREST WHEN USED FOR SEDATION. CONTINUOUS MONITORING AND PREPAREDNESS IS REQUIRED