Mid-Semester Test Revision Flashcards
Describe the venous drainage of the heart
Left side: Great cardiac vein
Posterior/inferior (alongside PDA): Middle cardiac vein
Right side: Small cardiac veins
Describe neurohumoral factors that control coronary artery flow
- Adrenaline
- Noradrenaline
- Acetylcholine
List some endothelial factors that play a role in coronary autoregulation
- Endothelin
- PGI2
- Nitric oxide
Relationship between resistance and conductance
They are the reciprocal of one another
Describe some factors that determine coronary blood flow
- Coronary venous PO2 (higher, less flow)
- Heart rate (higher, more flow)
List some metabolic factors that influence coronary vasomotor tone
- pH
- Adenosine
- K+
Effect of B2 activation on coronary arteries
Dilate
Effect of alpha receptor activation on coronary vessels
Constrict
Describe the migration of monocytes during atherosclerosis development
- Selectins slow
- While rolling, hits cchemokines
- Activates integrins
- Binds to VCAM/ICAM
- Transendothelial migration
- Becomes macrophage
How many true ribs are there on either side? Which are they?
T1-T7 (7)
How many false ribs are there on either side? Which are they? (not including floating ribs)
T8-T10 (3)
How many floating ribs are there on either side? Which are they?
T11-T12 (2)
List the four divisions of the mediastinum
Anterior, posterior, middle, superior
There is a transverse line that passes between the superior mediastinum and the other subdivisions. Where does it cut through anteriorly and posteriorly?
Anterior: Sternal angle
Posterior: T4/T5 intervertebral disc
List the five stages of change
- Pre-contemplation
- Contemplation
- Preparation-action
- Maintenance
- Relapse
Pectinate muscles vs trabeculae carnae
Pectinate: Atria
Tabecuale carnae: ventricles
Explain the diving reflex and its utility
- When the face comes into contact with water, heart rate slows down
- Blood is also redirected to vital organs, helping to preserve temp
- This allows the body to conserve oxygen, helping us to stay underwater for longer
Response of blood pressure and heart rate to exercise
- Increased sympathetic innervation (increased heart rate, vasodilation of muscles, constriction of others)
- Increased cardiac output (frank starling mechanism)
Mitral stenosis murmur sound
Lub Dub Durrrr
Loud S1 (thick mitral valve)
Low, mid-diastolic rumble because blood is slowly moving through
Mitral regurgitation murmur sound
Pan-systolic murmur
BURRRRRRR
Happens whole way through systole (high pitched due to high velocity)
Where does a mitral regurgitation murmur radiate?
Left axilla
Aortic stenosis murmur
Ejection systolic murmur
High pitched (high velocity)
Crescendo-decrescendo due to speed of blood flow
BURRR DUB
Where does aortic stenosis murmur radiate?
Carotids
Aortic regurgitation murmur
LUB TARRRR
Early diastolic murmur
How far above the clavicle does the parietal pleura reach?
2.5cm (subversion of multi-choice theory)
Cardiac blues vs depression
Cardiac blues: sudden changes in mood following cardiac event
Depression: Mental condition involving depressed mood or loss of pleasure/interest
According to the duke criteria, how many major/minor criteria do you need to be diagnosed?
- 2 Major, 1 Minor
- 1 Major, 3 Minor
- 5 Minor