Microbiology: Pandemic Flu/Antivirals/Opportunistic Infections Flashcards
Pandemic Flu:
What is the causative virus of flu?
What are the 3 anti genetically different flus?
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Pandemic Flu:
What is a natural reservoir of Influenza A?
What is H5N1?
What are the ideal situations for flu to grow?
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Pandemic Flu:
What are the RNA segments?
What is the effect of neuraminidase?
What is the effect of haemogglutimin?
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Pandemic Flu:
What is Antigenic drift?
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Antivirals:
What is the mechanism of action of for:
- Acyclovir
- Ganciclovir
What are the symptoms of CMV?
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Antivirals:
What is used if there is resistance to Ganciclovir?
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Antivirals:
What is the machoism of action of Cidofovir?
What is the effect of Foscarnet & Cidofovir?
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Antivirals:
What is the treatment of Herpes Simplex Infection (HSV)?
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Antivirals:
What is the treatment for CMV in BMT?
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Antivirals:
What is the treatment for Hepatitis B Virus (HBV) based on?
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Antivirals:
What are the goals in Hepatitis B treatment?
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Antivirals:
What are the drugs given in Hepatitis B treatment?
Nuceloside Analogues: “LEATT”
- Lamivudine
- Entecavir
- Adefovir dipivoxil
- Telbivudine
- Tenofovir (Inhibitor of reverse transcriptase, the rest are inhibitors of viral polymerase)
Preferred 1st line: “PET”
- PegINF alpha 2a
- Entecavir
- Tenofovir
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Antivirals:
What are the treatment goals in Hepatitis C treatment?
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Antivirals:
What are the genotypes affecting outcomes in Hepatitis C treatment?
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Antivirals:
What is is the treatment for Respiratory Viruses?
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Pandemic Flu:
What is Antigenic shift?
HA = Haemagglutinin
NA = Viral Neuraminidase
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Pandemic Flu:
What is the pathogenesis of Influenza?
HA = Haemagglutinin
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Pandemic Flu:
What is are the causes of severe outcomes in Flu?
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Pandemic Flu:
What are the antivirals used in Flu?
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Opportunistic Viral Infections:
What are the stages of PCR?
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Opportunistic Viral Infections:
Who is affected by opportunistic viral infections?
What are the types of immunodeficiencies?
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Opportunistic Viral Infections:
What are the 3 origins of opportunistic viral infections?
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Opportunistic Viral Infections:
Where do VZV/HSV remain dormant?
Where do EBV/CMV remain dormant?
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Antivirals:
What are the drugs given in Hepatitis C treatment?
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Opportunistic Viral Infections:
What are the most important characteristics of VZV?
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Opportunistic Viral Infections:
What are the most important characteristics of CMV?
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Opportunistic Viral Infections:
What are the most important characteristics of EBV?
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Opportunistic Viral Infections:
What are the most important characteristics of HHV8?
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Opportunistic Viral Infections:
What are the most important characteristics of HHV6?
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Opportunistic Viral Infections:
What are the most important characteristics of Adenovirus?
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Opportunistic Viral Infections:
What are the most important characteristics of Measles?
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