Histopathology: Liver Pathology Flashcards

1
Q

Liver Pathology:

What is the basic structure of the Liver?

A
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2
Q

Liver Pathology:

What are centrilobular and Periportal hepatocytes?

A
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3
Q

Liver Pathology:

What are the main functions of the liver?

A
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4
Q

Liver Pathology:

What is/are the definition and main features of Cirrhosis?

A
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5
Q

Liver Pathology:

What are the main causes of Cirrhosis?

A
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6
Q

Liver Pathology:

How can Cirrhosis be classified?

A
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7
Q

Liver Pathology:

What is the pathophysiology of Cirrhosis?

A
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8
Q

Liver Pathology:

What are the implications of different Child Pugh scores?

A
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9
Q

Liver Pathology:

What is the definition of Portal Hypertension?

What is it secondary to?

A
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10
Q

Liver Pathology:

What happens when portal pressure exceeds 10 to 12 mmHg?

A
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11
Q

Liver Pathology:

What are the causes of Portal Hypertension?

A
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12
Q

Liver Pathology:

What are the causes of Cirrhosis?

A
  • Alcoholic liver disease
    • Alcoholic hepatitis
    • Hepatic steatosis
    • Alcoholic Cirrhosis
  • Non Alcoholic Fatty Liver Disease
    • Simple steatosis
    • Non-Alcoholic fatty liver disease
  • Viral Hepatitis
  • Autoimmune hepatitis
    • Type 1
    • Type 2
  • Biliary causes of cirrhosis
    • Primary biliary cirrhosis
    • Primary Sclerosing cholangitis
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13
Q

Liver Pathology:

What is/are the definition and subtypes of Non Alcoholic Fatty Liver disease?

A
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14
Q

Liver Pathology:

What is/are the epidemiology, genetics, subtypes and treatment of Autoimmune Hepatitis?

A
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15
Q

Liver Pathology:

What is/are the definition, epidemiology, and investigations of Primary Biliary Cirrhosis (PBC)?

A
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16
Q

Liver Pathology:

What is/ are the histology, symptoms and treatment of Primary Biliary Cirrhosis (PBC)?

A
17
Q

Liver Pathology:

What is/are the definition and epidemiology of Primary Sclerosing Cholangitis (PSC)?

A
18
Q

Liver Pathology:

What are the investigations for Primary Sclerosing Cholangitis (PSC)?

A
19
Q

Liver Tumours:

What is the classification of liver tumours?

A
  • Benign
    • Hepatic adenoma
    • Haemangioma
  • Malignant
    • Hepatocellular
    • Carcinoma
    • Angiosarcoma
    • Hepatoblastoma
    • Cholangiosarcoma
    • Metastasis from other primary sources
20
Q

Liver Tumours:

What are the clinical features of Hepatic adenoma?

A
21
Q

Liver Tumours:

What are the clinical features of Haemangioma?

A
22
Q

Liver Tumours:

What are the clinical features of Hepatocellular Carcinoma?

A
23
Q

Liver Tumours:

What are the clinical features of Cholangiocarcinoma?

A
24
Q

Liver Tumours:

What are the clinical features of Metastases from other primary tumours?

A
25
Q

Modified Child Pugh Score:

What is the score of 1, score of 2 and score of 3 for:

  1. Ascites
  2. Encephalopathy
  3. Bilirubin
  4. Albumin
  5. Prothrombin time (sec > normal).
A
26
Q

Alcoholic Liver Disease:

What are the macroscopic and microscopic characteristics of Hepatic Steatosis (Fatty Liver)?

A
27
Q

Alcoholic Liver Disease:

What are the macroscopic and microscopic characteristics of Alcoholic hepatitis?

A
28
Q

Alcoholic Liver Disease:

What are the macroscopic and microscopic characteristics of Alcoholic Cirrhosis?

A
29
Q

Genetic Causes of Cirrhosis:

What is the incidence, age, pathophysiology and histology of Haemochromatosis?

A
30
Q

Genetic Causes of Cirrhosis:

What are the signs/symptoms and investigations of Haemochromatosis?

A
31
Q

Genetic Causes of Cirrhosis:

What is the incidence, age, pathophysiology and histology of Wilson’s Disease?

A
32
Q

Genetic Causes of Cirrhosis:

What are the signs/symptoms and investigations of Wilson’s Disease?

A
33
Q

Genetic Causes of Cirrhosis:

What is the incidence, age, pathophysiology and histology of Alpha 1 Antitrypsin Deficiency?

A
34
Q

Genetic Causes of Cirrhosis:

What are the signs/symptoms and investigations of Alpha 1 Antitrypsin Deficiency?

A