MicroBio Q's TF CH 5 Flashcards

1
Q

Ch 5

The genetic material found in a virion is usually what?

A

Either DNA or RNA

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2
Q

Ch 5

Viral particles are composed of what?

A

DNA or RNA, a coat of protein, and layers of carbohydrates, lipids and additional proteins

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3
Q

Ch 5

What is the best microscopic methods for studying viruses?

A

Electron microscopy

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4
Q

Ch 5

What is the function of the viral capsid?

A

To the protect the viral genome

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5
Q

Ch 5

The Tobacco mosaic virus exhibits which type of capsid symmetry?

A

Helical

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6
Q

Ch 5

An example of a virus that exhibits binal symmetry is known as what?

A

Bacteriophages

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7
Q

Ch 5

Viral spikes or peplomers are involved in what?

A

Attachment

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8
Q

Ch 5

Which structures are associated with the influenza virus?

A

Neuraminidase enzyme, hemagglutinin protein, and glycoproteins

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9
Q

Ch 5

The most common viral nucleic acid types are what?

A

dsDNA and ssRNA

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10
Q

Ch 5

What is the first step in the generalized viral life cycle?

A

Attachment of virus to host cell

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11
Q

Ch 5

What is viral host specificity most likely attributed to?

A

Interaction between receptors on the surface of the host cell and ligands on the surface of virions

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12
Q

Ch 5

Which mechanisms do eukaryotic viruses enter host cells through?

A

Through fusion of the viral envelope with the host cell membrane, entry by endocytosis, and injection of nucleic acid

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13
Q

Ch 5

Which types of viruses must carry their own replication enzymes in their nucleocapsid?

A

RNA viruses only

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14
Q

Ch 5

Where does the energy that is required for bacteriophage assembly come from?

A

Host metabolic activity

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15
Q

Ch 5

What is a common virion release method observed in enveloped viruses?

A

Budding

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16
Q

Ch 5

What is the name of the relationship with the host cell in which the virus remains within the host without destroying it called?

A

Lysogeny

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17
Q

Ch 5

What does an advantage of lysogeny to the host include?

A

Resistance to superinfection

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18
Q

Ch 5

When more phage are present in the environment than there are host cells, which type of host relationship is most desirable?

A

Lysogenic preferred

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19
Q

Ch 5

What are microscopic and/or macroscopic damages to host cells caused by eukaryotic viruses called?

A

Cytopathic effects

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20
Q

Ch 5

What is the name for a type of viral infection in which there is a low release of virions without cell death?

A

Chronic infection

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21
Q

Ch 5

What cellular genes required for normal growth, but when mutated or overexposed, cause carcinogenesis?

A

Proto-oncogenes

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22
Q

Ch 5

Which of the following viruses is NOT definitely linked to causing cancer in humans?

A

Rabies virus

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23
Q

Ch 5

Which methods can be used to cultivate plant viruses?

A

Grow in cultures of plant cells lacking cell walls, mechanically break leaves to expose cells to infection, or graft diseased part onto a healthy plant

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24
Q

Ch 5

What can be used to determine direct counts of viral particles?

A

Epifluorescence microscopy

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25
# Ch 5 What is an indirect method of counting animal viruses?
Hemagglutination assay
26
# Ch 5 The number of plaque-forming units (PFUs) is calculated from a viral plaque assay by.....?
Multiplying the number of plaques per volume by the dilution
27
# Ch 5 What is teh dilution taht contains the number of viral cells large enough to destroy 50% of the host cells or organisms called?
The lethal dose
28
# Ch 5 What are infectious RNAs that primarily infect plants called?
Viroids
29
# Ch 5 What are infectious proteins responsible for bovine spongiform encephalopathy called?
Prions
30
# Ch 5 Viruses are considered to be living organisms
FALSE
31
# Ch 5 Scientists classify viruses based on genome structure, life cycles, morphology, and genetic relatedness
TRUE
32
# Ch 5 Most viruses are approximately the same size as bacteria (0.2 to 2 micrometers)
FALSE
33
# Ch 5 Hos-independent growth has never been observed in either the bacterial or archaeal viruses
FALSE
34
# Ch 5 The size of a helical capsid is influenced by both its protomores and the nucleic acids enclosed within the capsid
TRUE
35
# Ch 5 The icosohedral capsid maximizes efficiency and requires few genes for its coding
TRUE
36
# Ch 5 An envelope is present in all viruses
FALSE
37
# Ch 5 Spikes can be used to identify many types of viruses
TRUE
38
# Ch 5 All virions lack enzymes
FALSE
39
# Ch 5 Most DNA viruses use dsDNA as their genetic material
TRUE
40
# Ch 5 Many RNA viruses have segmented genomes with each segment coding for a protein
TRUE
41
# Ch 5 Viral attachment to the host cell is a random process
FALSE
42
# Ch 5 Variation in receptors used by a virus for attachment is partly responsible for host specificity
TRUE
43
# Ch 5 All viruses inject their nucleic acid into the cytoplasm of their host, leaving the capsid outside and attached to the cell wall
FALSE
44
# Ch 5 Human immunodeficiency virus (HIV) enters the host cell by fusing directly with the host cell plasma membrane
TRUE
45
# Ch 5 DNA and RNA viruses replicate using the same processes
FALSE
46
# Ch 5 Bacteriophages are assembled in the host cytoplasm
TRUE
47
# Ch 5 All animal viruses are assembled in the cytoplasm
FALSE
48
# Ch 5 Many nonenveloped viruses lyse their host cells at the end of the intracellular phase
TRUE
49
# Ch 5 When viral cells are released via budding, the host cell may survive and continue releasing virions for some time
TRUE
50
# Ch 5 Actin filaments in the cytoskeleton can aid in the release of eukaryotic viruses
TRUE
51
# Ch 5 Temperate phages must release from the host cell via lysis
FALSE
52
# Ch 5 Temperate phages can integrate their genome with the host genome
TRUE
53
# Ch 5 Host cells that are infected with a temperate virus cannot be infected by other virions of the same type
TRUE
54
# Ch 5 temperate phages can alternate between lysogenic and lytic stages
TRUE
55
# Ch 5 Lysogeny enables survival of host cells in an environment with low multiplicity of infection (MOI)
FALSE
56
# Ch 5 A chronic infection is a situation in which a virus slowly releases virions without killing the cell
TRUE
57
# Ch 5 Most human viruses associated with cancer have dsDNA genomes
TRUE
58
# Ch 5 Some strains of human papillomavirus (HPV) can cause cervical caner
TRUE
59
# Ch 5 Tumor activator proteins promote formation of tumors in human dsDNA viruses
FALSE
60
# Ch 5 Viruses are easily cultivate in agars and broths, much like bacteria
FALSE
61
# Ch 5 Plaque assays determine viral numbers based on infectivity of the virus
TRUE
62
# Ch 5 The number of plaque-forming units (PFUs) is equal to the number of viruses because all virions are infective
FALSE
63
# Ch 5 The infectious dose (ID60) of a virus is the dose that, when given to a number of hosts, causes and infection of 50% of the hosts under particular conditions
TRUE
64
# Ch 5 Viroids, or infectious RNAs, cause many important plant diseases
TRUE