MICROBIAL METABOLISM Flashcards
set of chemical reactions that occur in living organisms to maintain life
metabolism
breakdown complex molecules in simpler ones, often releasing energy in the process
catabolism
refers to the synthesis of complex molecules from simpler ones, usually requiring energy input
anabolism
production of precursors such as amino acids, monosaccharides, and nucleotides
stage 1
use energy from ATP to turn the precursors into reactive form
stage 2
the assembly of these activated precursors into complex molecules such as proteins, polysaccharides, lipids, and nucleic acids
stage 3
biological catalysts that accelerate chemical reactions in living organisms
enzymes
involve the binding of an enzyme to its substrates at the enzyme’s active site
enzyme-substrate interactions
catalyze oxidation-reduction reactions
transfer electrons from one substrate to another
oxidoreductases
transfer functional groups between molecules
transferases
catalyze hydrolysis reactions
cleave bonds on molecules with the addition of water
hydrolases
remove groups from or add groups to substrates without hydrolysis or oxidation
lyases
catalyze isomerization reactions
isomerases
catalyze the joining of two molecules, often coupled with the hydrolysis of ATP
ligases
regulatory molecules bind to allosteric sites on the enzyme, altering its activity
allosteric regulation
enzyme activity is altered by the addition or removal of chemical groups
covalent modification
the end product of a metabolic pathway inhibits and enzyme involved in an earlier step, regulating overall pathway
feedback inhibition
gene expression controls the synthesis of enzymes, with induction increasing enzyme production and repression decreasing it in response to environmental conditions
induction or repression
reactant molecules acted on by an enzyme
substrates
consist of protein alone
simple enzyme