Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Hematology review > Microangiopathic Hemolytic Anemia > Flashcards

Microangiopathic Hemolytic Anemia Flashcards

1
Q

What is the mechanism of action of Caplacizumab?

A

Binds to the A1 domain of vWF inhibiting interaction w/platelets, thereby inhibiting interaction with platelets and reducing platelet adhesion/consumption.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the mechanism of action of Eculizumab?

A

It binds to C5 thus inhibiting the cleavage of C5 to C5a and C5b to form the C5b-9 complex needed for lysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

When giving Eculizumab what is needed first?

A

Patients must get vaccinated against encapsulated organisms (N. Gonorrhea, H. flu, Strep Pneumonaie). Will need abx for 2 weeks after starting.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly

Hematology review (34 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions