ITP Flashcards
1
Q
What is the mechanism of action of Fosamatinib? What is the indication?
A
It’s an oral (SYK) spleen tyrosine kinase inhibitor. You only use it for patients who have not had a previous response to prior therapy
2
Q
What should be monitored while on Fosmatinib?
A
You must monitor BP, LFTs, diarrhea, and neutropenia. Avoid use with CYP3A4 inhibitors.
3
Q
Before a patient undergoes splenectomy what vaccinations should they receive?
A
H. Flu, N. Meningitides, and S. Pneumoniae